Next Article in Journal
Vitamin D and Immunity in Infants and Children
Next Article in Special Issue
It’s No Has Bean: A Review of the Effects of White Kidney Bean Extract on Body Composition and Metabolic Health
Previous Article in Journal
Calculating Protein Content of Expressed Breast Milk to Optimize Protein Supplementation in Very Low Birth Weight Infants with Minimal Effort—A Secondary Analysis
Previous Article in Special Issue
Decreased Consumption of Added Fructose Reduces Waist Circumference and Blood Glucose Concentration in Patients with Overweight and Obesity. The DISFRUTE Study: A Randomised Trial in Primary Care
Article

Oils’ Impact on Comprehensive Fatty Acid Analysis and Their Metabolites in Rats

Department of Bromatology, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(5), 1232; https://doi.org/10.3390/nu12051232
Received: 6 April 2020 / Revised: 20 April 2020 / Accepted: 24 April 2020 / Published: 27 April 2020
(This article belongs to the Special Issue Dietary Modifications and Human Health)
Fatty acids, especially polyunsaturated, and their metabolites (eicosanoids) play many pivotal roles in human body, influencing various physiological and pathological processes. The aim of the study was to evaluate the effect of supplementation with edible oils diverse in terms of fatty acid composition on fatty acid contents, activities of converting their enzymes, and on lipoxygenase metabolites of arachidonic and linoleic acids (eicosanoids) in rat serum. Female Sprague-Dawley rats divided into seven groups were used in the study. Animals from six groups were fed one of oils daily (carotino oil, made up by combining of red palm oil and canola oil, linseed oil, olive oil, rice oil, sesame oil, or sunflower oil). One group received a standard diet only. Fatty acids were determined using gas chromatography with flame ionization detection. Eicosanoids—hydroxyeicosatetraenoic (HETE) and hydroxyoctadecadienoic acids (HODE) were extracted using a solid-phase extraction method and analyzed with HPLC. Vegetable oils given daily to rats caused significant changes in serum fatty acid profile and eicosanoid concentrations. Significant differences were also found in desaturases’ activity, with the linseed and olive oil supplemented groups characterized by the highest D6D and D5D activity. These findings may play a significant role in various pathological states. View Full-Text
Keywords: fatty acid composition; vegetable oils; desaturases; arachidonic and linoleic acid metabolites; hydroxyeicosatetraenoic acids; hydroxyoctadecadienoic acids fatty acid composition; vegetable oils; desaturases; arachidonic and linoleic acid metabolites; hydroxyeicosatetraenoic acids; hydroxyoctadecadienoic acids
Show Figures

Figure 1

MDPI and ACS Style

Stawarska, A.; Jelińska, M.; Czaja, J.; Pacześniak, E.; Bobrowska-Korczak, B. Oils’ Impact on Comprehensive Fatty Acid Analysis and Their Metabolites in Rats. Nutrients 2020, 12, 1232. https://doi.org/10.3390/nu12051232

AMA Style

Stawarska A, Jelińska M, Czaja J, Pacześniak E, Bobrowska-Korczak B. Oils’ Impact on Comprehensive Fatty Acid Analysis and Their Metabolites in Rats. Nutrients. 2020; 12(5):1232. https://doi.org/10.3390/nu12051232

Chicago/Turabian Style

Stawarska, Agnieszka; Jelińska, Małgorzata; Czaja, Julia; Pacześniak, Ewelina; Bobrowska-Korczak, Barbara. 2020. "Oils’ Impact on Comprehensive Fatty Acid Analysis and Their Metabolites in Rats" Nutrients 12, no. 5: 1232. https://doi.org/10.3390/nu12051232

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop