Next Article in Journal
Changes in Intestinal Microbiota and Predicted Metabolic Pathways During Colonic Fermentation of Mango (Mangifera indica L.)—Based Bar Indigestible Fraction
Next Article in Special Issue
Anti-Inflammatory and Antioxidant Effects of Anthocyanins of Trifolium pratense (Red Clover) in Lipopolysaccharide-Stimulated RAW-267.4 Macrophages
Previous Article in Journal
Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes
Previous Article in Special Issue
Dietary Habits and Dietary Antioxidant Intake Are Related to Socioeconomic Status in Polish Adults: A Nationwide Study
Open AccessReview

Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease

1
Graduate Program in Health Sciences (Cardiology), Institute of Cardiology of Rio Grande do Sul/University Foundation of Cardiology (IC/FUC), Princesa Isabel Avenue, 395, Porto Alegre, 90040-371 Rio Grande do Sul, Brazil
2
HCor Research Institute, Coracao Hospital (IP-HCor), Abílio Soares Street, 250, 04004-05 São Paulo, Brazil
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(3), 682; https://doi.org/10.3390/nu12030682
Received: 31 January 2020 / Revised: 25 February 2020 / Accepted: 2 March 2020 / Published: 3 March 2020
(This article belongs to the Special Issue Dietary Antioxidants for Human Health)
Atherosclerosis is related to fat accumulation in the arterial walls and vascular stiffening, and results in acute coronary syndrome which is commonly associated with acute myocardial infarction. Oxidative stress participates in the pathogenesis of atherosclerosis. Thus, the inclusion of food sources of dietary antioxidants, such as different kinds of nuts, may improve biomarkers related to oxidative stress, contributing to a possible reduction in atherosclerosis progression. This article has briefly highlighted the interaction between oxidative stress, atherosclerosis, and cardiovascular disease, in addition to the effect of the consumption of different nuts and related dietary antioxidants—like polyphenols and vitamin E—on biomarkers of oxidative stress in primary and secondary cardiovascular prevention. Studies in vitro suggest that nuts may exert antioxidant effects by DNA repair mechanisms, lipid peroxidation prevention, modulation of the signaling pathways, and inhibition of the MAPK pathways through the suppression of NF-κB and activation of the Nrf2 pathways. Studies conducted in animal models showed the ability of dietary nuts in improving biomarkers of oxidative stress, such as oxLDL and GPx. However, clinical trials in humans have not been conclusive, especially with regards to the secondary prevention of cardiovascular disease. View Full-Text
Keywords: oxidative stress; antioxidants; nuts; cardiovascular diseases oxidative stress; antioxidants; nuts; cardiovascular diseases
Show Figures

Figure 1

MDPI and ACS Style

Lorenzon dos Santos, J.; Schaan de Quadros, A.; Weschenfelder, C.; Bueno Garofallo, S.; Marcadenti, A. Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease. Nutrients 2020, 12, 682. https://doi.org/10.3390/nu12030682

AMA Style

Lorenzon dos Santos J, Schaan de Quadros A, Weschenfelder C, Bueno Garofallo S, Marcadenti A. Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease. Nutrients. 2020; 12(3):682. https://doi.org/10.3390/nu12030682

Chicago/Turabian Style

Lorenzon dos Santos, Julia; Schaan de Quadros, Alexandre; Weschenfelder, Camila; Bueno Garofallo, Silvia; Marcadenti, Aline. 2020. "Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease" Nutrients 12, no. 3: 682. https://doi.org/10.3390/nu12030682

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop