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Article

Malnutrition Prevalence according to the GLIM Criteria in Head and Neck Cancer Patients Undergoing Cancer Treatment

1
Nutrition and Speech Pathology Department, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia
2
Allied Health Department, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia
3
Physiotherapy Department, The University of Melbourne, Parkville, VIC 3052, Australia
4
Department of Surgery, Western Health, The University of Melbourne, Melbourne, VIC 3000, Australia
5
Department of Nutrition and Dietetics, Western Health, Footscray, VIC 3011, Australia
6
Institute for Physical Activity and Nutrition, Deakin University, Geelong, VIC 3220, Australia
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(11), 3493; https://doi.org/10.3390/nu12113493
Received: 9 October 2020 / Revised: 4 November 2020 / Accepted: 11 November 2020 / Published: 13 November 2020
Malnutrition is highly prevalent in people with head and neck cancer (HCN) and is associated with poorer outcomes. However, variation in malnutrition diagnostic criteria has made translation of the most effective interventions into practice challenging. This study aimed to determine the prevalence of malnutrition in a HNC population according to the Global Leadership Initiative on Malnutrition (GLIM) criteria and assess inter-rater reliability and predictive validity. A secondary analysis of data available for 188 patients with HNC extracted from two cancer malnutrition point prevalence studies was conducted. A GLIM diagnosis of malnutrition was assigned when one phenotypic and one etiologic criterion were present. Phenotypic criteria were ≥5% unintentional loss of body weight, body mass index (BMI), and subjective evidence of muscle loss. Etiologic criteria were reduced food intake, and presence of metastatic disease as a proxy for inflammation. The prevalence of malnutrition was 22.6% (8.0% moderately malnourished; 13.3% severely malnourished). Inter-rater reliability was classified as excellent for the GLIM criteria overall, as well as for each individual criterion. A GLIM diagnosis of malnutrition was found to be significantly associated with BMI but was not predictive of 30 day hospital readmission. Further large, prospective cohort studies are required in this patient population to further validate the GLIM criteria. View Full-Text
Keywords: head and neck neoplasms; malnutrition; nutrition head and neck neoplasms; malnutrition; nutrition
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MDPI and ACS Style

Steer, B.; Loeliger, J.; Edbrooke, L.; Deftereos, I.; Laing, E.; Kiss, N. Malnutrition Prevalence according to the GLIM Criteria in Head and Neck Cancer Patients Undergoing Cancer Treatment. Nutrients 2020, 12, 3493. https://doi.org/10.3390/nu12113493

AMA Style

Steer B, Loeliger J, Edbrooke L, Deftereos I, Laing E, Kiss N. Malnutrition Prevalence according to the GLIM Criteria in Head and Neck Cancer Patients Undergoing Cancer Treatment. Nutrients. 2020; 12(11):3493. https://doi.org/10.3390/nu12113493

Chicago/Turabian Style

Steer, Belinda, Jenelle Loeliger, Lara Edbrooke, Irene Deftereos, Erin Laing, and Nicole Kiss. 2020. "Malnutrition Prevalence according to the GLIM Criteria in Head and Neck Cancer Patients Undergoing Cancer Treatment" Nutrients 12, no. 11: 3493. https://doi.org/10.3390/nu12113493

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