Next Article in Journal
Time-Restricted Eating as a Nutrition Strategy for Individuals with Type 2 Diabetes: A Feasibility Study
Previous Article in Journal
Diet Quality, Saturated Fat and Metabolic Syndrome
Previous Article in Special Issue
Impact of Clinical Markers of Nutritional Status and Feeding Jejunostomy Use on Outcomes in Esophageal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy
Open AccessReview

Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis

1
Faculty of Health Sciences, OsloMet—Oslo Metropolitan University, 0130 Oslo, Norway
2
Regional Advisory Unit for Palliative Care, Department of Oncology, Oslo University Hospital, 0424 Oslo, Norway
3
Unicare Røros, Øverhagaen 15, 7374 Røros, Norway
4
Department of Cancer Research and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway
5
Cancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7006 Trondheim, Norway
6
National Advisory Unit on Late Effects after Cancer Treatment, Department of Oncology, Oslo University Hospital, 0424 Oslo, Norway
7
Department for Clinical Service, Division of Cancer Medicine, Oslo University Hospital, 0424 Oslo, Norway
8
Oslo Centre of Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, 0424 Oslo, Norway
9
Center for Crisis Psychology, Faculty of Psychology, University of Bergen, 5020 Bergen, Norway
10
Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, The Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(11), 3233; https://doi.org/10.3390/nu12113233
Received: 11 September 2020 / Revised: 14 October 2020 / Accepted: 20 October 2020 / Published: 22 October 2020
(This article belongs to the Special Issue Clinical Nutrition for Cancer Patients)
The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck cancer on body composition, objectively measured physical function and nutritional status. Systematic electronic searches were conducted in MEDLINE (PubMed interface), EMBASE (Ovid interface), CINAHL (EBSCO interface) and Cochrane Library (Wiley interface). We identified 13 randomized controlled trials (RCTs) that included 858 patients. For body composition, using only nutrition as intervention, a significant difference between treatment and control group were observed (SMD 0.42 (95CI 0.23–0.62), p < 0.001). Only pilot RCTs investigated combination treatment and no significant difference between the treatment and control groups were found (SMD 0.21 (95CI −0.16–0.58), p = 0.259). For physical function, a significant difference between treatment and control group with a better outcome for the treatment group were observed (SMD 0.78 (95CI 0.51–1.04), p < 0.001). No effects on nutritional status were found. This meta-analysis found significantly positive effects of nutrition and physical exercise interventions alone in favor of the treatment groups. No effects in studies with combined interventions were observed. Future full-scaled RCTs combining nutrition and physical exercise is warranted. View Full-Text
Keywords: head and neck neoplasms; nutrition; physical exercise; radiotherapy; meta-analysis; nutritional status; physical function; body composition head and neck neoplasms; nutrition; physical exercise; radiotherapy; meta-analysis; nutritional status; physical function; body composition
Show Figures

Figure 1

MDPI and ACS Style

Bye, A.; Sandmael, J.A.; Stene, G.B.; Thorsen, L.; Balstad, T.R.; Solheim, T.S.; Pripp, A.H.; Oldervoll, L.M. Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis. Nutrients 2020, 12, 3233.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop