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Review

Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human

1
College of Pharmacy, Ajou University, Suwon 16499, Korea
2
Research Institute of Pharmaceutical Sciences and Technology, Ajou University, Suwon 16499, Korea
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(10), 3080; https://doi.org/10.3390/nu12103080
Received: 26 August 2020 / Revised: 2 October 2020 / Accepted: 4 October 2020 / Published: 9 October 2020
(This article belongs to the Special Issue Coffee and Caffeine Consumption for Human Health)
Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia, and gastrointestinal disorders. Recently, there has been increasing interest in the effect of caffeine consumption as a protective factor or risk factor for neurological and psychiatric disorders. Currently, the importance of personalized medicine is being emphasized, and research on sex/gender differences needs to be conducted. Our review focuses on the effect of caffeine consumption on several neurological and psychiatric disorders with respect to sex differences to provide a better understanding of caffeine use as a risk or protective factor for those disorders. The findings may help establish new strategies for developing sex-specific caffeine therapies. View Full-Text
Keywords: caffeine; neurological and psychiatric disorders; sleep disorder; stroke; dementia; depression; sex differences caffeine; neurological and psychiatric disorders; sleep disorder; stroke; dementia; depression; sex differences
MDPI and ACS Style

Jee, H.J.; Lee, S.G.; Bormate, K.J.; Jung, Y.-S. Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human. Nutrients 2020, 12, 3080. https://doi.org/10.3390/nu12103080

AMA Style

Jee HJ, Lee SG, Bormate KJ, Jung Y-S. Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human. Nutrients. 2020; 12(10):3080. https://doi.org/10.3390/nu12103080

Chicago/Turabian Style

Jee, Hye J., Sang G. Lee, Katrina J. Bormate, and Yi-Sook Jung. 2020. "Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human" Nutrients 12, no. 10: 3080. https://doi.org/10.3390/nu12103080

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