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Coffee Intake and Obesity: A Meta-Analysis

1
Dartmouth College, Hanover, NH 03755, USA
2
Department of Food Science and Biotechnology, Dongguk University, Goyang 10325, Korea
3
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02138, USA
4
College of Health Sciences, Korea University, Seoul 02841, Korea
5
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02138, USA
*
Authors to whom correspondence should be addressed.
These authors contributed equally as co-first authors.
Nutrients 2019, 11(6), 1274; https://doi.org/10.3390/nu11061274
Received: 27 April 2019 / Revised: 19 May 2019 / Accepted: 29 May 2019 / Published: 5 June 2019
(This article belongs to the Special Issue Targeted Nutrition in Chronic Disease)
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Abstract

Many studies have explored the relationship between coffee—one of the most commonly consumed beverages today—and obesity. Despite inconsistent results, the relationship has not been systematically summarized. Thus, we conducted a meta-analysis by compiling data from 12 epidemiologic studies identified from PubMed and Embase through February 2019. The included studies assessed obesity by body mass index (BMI, a measure of overall adiposity) or waist circumference (WC, a measure of central adiposity); analyzed the measure as a continuous outcome or binary outcome. Using random effects model, weighted mean difference (WMD) and 95% confidence interval (CI) were obtained for continuous outcomes; summary relative risk (RR) and 95% CI for the highest vs. lowest categories of coffee intake were estimated for binary outcome. For BMI, WMD was −0.08 (95% CI −0.14, −0.02); RR was 1.49 (95% CI 0.97, 2.29). For WC, WMD was −0.27 (95% CI −0.51, −0.02) and RR was 1.07 (95% CI 0.84, 1.36). In subgroup analysis by sex, evidence for an inverse association was more evident in men, specifically for continuous outcome, with WMD −0.05 (95% CI −0.09, −0.02) for BMI and −0.21 (95% CI −0.35, −0.08) for WC. Our meta-analysis suggests that higher coffee intake might be modestly associated with reduced adiposity, particularly in men. View Full-Text
Keywords: coffee intake; obesity; adiposity; body mass index; waist circumference; meta-analysis coffee intake; obesity; adiposity; body mass index; waist circumference; meta-analysis
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Lee, A.; Lim, W.; Kim, S.; Khil, H.; Cheon, E.; An, S.; Hong, S.; Lee, D.H.; Kang, S.-S.; Oh, H.; Keum, N.; Hsieh, C.-C. Coffee Intake and Obesity: A Meta-Analysis. Nutrients 2019, 11, 1274.

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