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Nutrients 2018, 10(7), 873;

Limited Benefit of Fish Consumption on Risk of Hip Fracture among Men in the Community-Based Hordaland Health Study

Department of Clinical Science, Faculty of Medicine, University of Bergen, 5020 Bergen, Norway
Center for Disease Burden, Norwegian Institute of Public Health, 5020 Bergen, Norway
Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 3017 Oslo, Norway
Center for Nutrition, Department of Clinical Medicine, Faculty of Medicine, University of Bergen, 5020 Bergen, Norway
Laboratory Medicine and Pathology, Haukeland University Hospital, 5021 Bergen, Norway
Department of Global Public Health and Primary Care, University of Bergen, 5021 Bergen, Norway
Author to whom correspondence should be addressed.
Received: 20 June 2018 / Accepted: 3 July 2018 / Published: 6 July 2018
(This article belongs to the Special Issue Fish and Meat Consumption: Risks and Benefits)
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Hip fractures have a high prevalence worldwide. Few studies have investigated whether fish consumption is associated with risk of hip fractures. The objective of the present study was to investigate the effect of fish intake on the subsequent risk of a hip fracture because of the low number of studies on this topic. A community-based prospective cohort study of 2865 men and women from Hordaland county in Norway, born between 1925–1927 and enrolled in the study in 1997–1999. Information on hip fracture cases was extracted from hospital records until 31 December 2009. Baseline information on the intake of fish was obtained from a semi-quantitative food frequency questionnaire. Cox proportional hazard regression models with death as a competing risk were used to evaluate the association of fish intake with risk of hip fracture. During a mean (SD) follow-up time of 9.6 (2.7) years, 226 hip fractures (72 in men, 154 in women) were observed. The mean (SD) fish intake was 48 (25) g/1000 kcal. The association between fish intake and risk of hip fracture was not linear and displayed a threshold, with low intake of fish being associated with an increased risk of hip fracture in men (HR (Hazard Ratio) = 1.84, 95% CI 1.10, 3.08). In this community-based prospective study of men and women, a low intake of fish was associated with the risk of a hip fracture in men. View Full-Text
Keywords: diet; food frequency questionnaire; fish intake; hip fractures diet; food frequency questionnaire; fish intake; hip fractures

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Rosendahl-Riise, H.; Sulo, G.; Karlsson, T.; Drevon, C.A.; Dierkes, J.; Tell, G.S. Limited Benefit of Fish Consumption on Risk of Hip Fracture among Men in the Community-Based Hordaland Health Study. Nutrients 2018, 10, 873.

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