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Testing the Predictive Validity of the Healthy Eating Index-2015 in the Multiethnic Cohort: Is the Score Associated with a Reduced Risk of All-Cause and Cause-Specific Mortality?

1
University of Hawaii Cancer Center, Honolulu, HI 96813, USA
2
University of Memphis, Memphis, TN 38152, USA
3
University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA
4
Division of Cancer Control and Population Sciences, Bethesda, MD 20892, USA
*
Author to whom correspondence should be addressed.
Nutrients 2018, 10(4), 452; https://doi.org/10.3390/nu10040452
Received: 8 February 2018 / Revised: 30 March 2018 / Accepted: 3 April 2018 / Published: 5 April 2018
(This article belongs to the Special Issue Dietary Patterns, Diet Quality and Human Health)
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Abstract

The Healthy Eating Index-2015 (HEI-2015) was created to assess conformance of dietary intake with the Dietary Guidelines for Americans (DGA) 2015–2020. We assessed the association between the HEI-2015 and mortality from all-cause, cardiovascular disease (CVD), and cancer in the Multiethnic Cohort (MEC). White, African American, Native Hawaiian, Japanese American, and Latino adults (n > 215,000) from Hawaii and California completed a quantitative food-frequency questionnaire at study enrollment. HEI-2015 scores were divided into quintiles for men and women. Radar graphs were used to demonstrate how dietary components contributed to HEI-2015 scores. Mortality was documented over 17–22 years of follow-up. Hazard ratios (HRs) and 95% confidence intervals (CIs) were computed using Cox proportional hazards models. High HEI-2015 scores were inversely associated with risk of mortality from all-cause, CVD, and cancer for men and women (p-trend <0.0001 for all models). For men, the HRs (CIs) for all-cause, CVD, and cancer comparing the highest to the lowest quintile were 0.79 (0.76, 0.82), 0.76 (0.71, 0.82), and 0.80 (0.75, 0.87), respectively. For women, the HRs were 0.79 (0.76, 0.82), 0.75 (0.70, 0.81), and 0.84 (0.78, 0.91), respectively. These results, in a multiethnic population, demonstrate that following a diet aligned with the DGAs 2015–2020 recommendations is associated with lower risk of mortality from all-cause, CVD, and cancer. View Full-Text
Keywords: Healthy Eating Index; Dietary Guidelines for Americans; dietary index; multiethnic; mortality risk; Dietary Practices Methods Project; prospective cohort study Healthy Eating Index; Dietary Guidelines for Americans; dietary index; multiethnic; mortality risk; Dietary Practices Methods Project; prospective cohort study
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Panizza, C.E.; Shvetsov, Y.B.; Harmon, B.E.; Wilkens, L.R.; Le Marchand, L.; Haiman, C.; Reedy, J.; Boushey, C.J. Testing the Predictive Validity of the Healthy Eating Index-2015 in the Multiethnic Cohort: Is the Score Associated with a Reduced Risk of All-Cause and Cause-Specific Mortality? Nutrients 2018, 10, 452.

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