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Nutrients 2018, 10(11), 1693;

Rationale of Probiotic Supplementation during Pregnancy and Neonatal Period

Neonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, “Aldo Moro” University of Bari, P.zza Giulio Cesare 11, 70124 Bari, Italy
Section of Microbiology, Department of Public Health and Infectious Diseases, Sapienza University, Piazzale Aldo Moro 5, 00185 Rome, Italy
Department of Interdisciplinary Medicine, “Aldo Moro” University of Bari, 70100 Bari, Italy
Author to whom correspondence should be addressed.
Received: 24 September 2018 / Revised: 31 October 2018 / Accepted: 3 November 2018 / Published: 6 November 2018
(This article belongs to the Special Issue Probiotics and Prebiotics in Pediatrics)
Full-Text   |   PDF [291 KB, uploaded 6 November 2018]


Probiotics are living microorganisms that confer a health benefit when administered in adequate amounts. It has been speculated that probiotics supplementation during pregnancy and in the neonatal period might reduce some maternal and neonatal adverse outcomes. In this narrative review, we describe the rationale behind probiotic supplementation and its possible role in preventing preterm delivery, perinatal infections, functional gastrointestinal diseases, and atopic disorders during early life. View Full-Text
Keywords: “Probiotics”[Mesh]; “Pregnancy”[Mesh]; “Infant, Newborn”[Mesh] “Probiotics”[Mesh]; “Pregnancy”[Mesh]; “Infant, Newborn”[Mesh]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Baldassarre, M.E.; Palladino, V.; Amoruso, A.; Pindinelli, S.; Mastromarino, P.; Fanelli, M.; Di Mauro, A.; Laforgia, N. Rationale of Probiotic Supplementation during Pregnancy and Neonatal Period. Nutrients 2018, 10, 1693.

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