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Habitual Tea Consumption and Risk of Fracture in 0.5 Million Chinese Adults: A Prospective Cohort Study

Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China
Chinese Academy of Medical Sciences, Beijing 100191, China
Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX1 2JD, UK
Pengzhou Center for Disease Control and Prevention, Pengzhou 611930, Sichuan, China
NCDs Prevention and Control Department, Liuzhou Center for Disease Control and Prevention, Liuzhou 545007, Guangxi, China
China National Center for Food Safety Risk Assessment, Beijing 100191, China
Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education, Beijing 100191, China
Peking University Institute of Environmental Medicine, Beijing 100191, China
Author to whom correspondence should be addressed.
The members of steering committee and collaborative group are listed in the Acknowledgements.
Nutrients 2018, 10(11), 1633;
Received: 27 September 2018 / Revised: 20 October 2018 / Accepted: 23 October 2018 / Published: 2 November 2018
(This article belongs to the Special Issue Tea in Health and Disease)
PDF [423 KB, uploaded 2 November 2018]


Background: Tea consumption may have favorable effects on risk of fracture. However, little is known about such association in Chinese adults. The aim of this study was to examine the association between tea consumption and risk of hospitalized fracture in Chinese adults. Methods: The present study included 453,625 participants from the China Kadoorie Biobank (CKB). Tea consumption was self-reported at baseline. Hospitalized fractures were ascertained through linkage with local health insurance claim databases. The results: During a median of 10.1 years of follow-up, we documented 12,130 cases of first-time any fracture hospitalizations, including 1376 cases of hip fracture. Compared with never tea consumers, daily tea consumption was associated with lower risk of any fracture (hazard ratio (HR): 0.88; 95% confidence interval (CI): 0.83, 0.93). Statistically significant reduced risk of hip fracture was shown among daily consumers who most commonly drank green tea (HR: 0.80; 95% CI: 0.65, 0.97) and those who had drunk tea for more than 30 years (HR: 0.68; 95% CI: 0.52, 0.87). Our conclusions: Habitual tea consumption was associated with moderately decreased risk of any fracture hospitalizations. Participants with decades of tea consumption and those who preferred green tea were also associated with lower risk of hip fracture. View Full-Text
Keywords: tea consumption; fracture; cohort study tea consumption; fracture; cohort study

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Shen, Q.; Yu, C.; Guo, Y.; Bian, Z.; Zhu, N.; Yang, L.; Chen, Y.; Luo, G.; Li, J.; Qin, Y.; Chen, J.; Chen, Z.; Lv, J.; Li, L.; On behalf of the China Kadoorie Biobank Collaborative Group. Habitual Tea Consumption and Risk of Fracture in 0.5 Million Chinese Adults: A Prospective Cohort Study. Nutrients 2018, 10, 1633.

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