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Review

IoT Applications and Challenges in Global Healthcare Systems: A Comprehensive Review

by
Fadele Ayotunde Alaba
1,*,
Alvaro Rocha
2,*,
Hakeem Adewale Sulaimon
1 and
Owamoyo Najeem
1
1
Department of Computer Science, Federal University of Education, Zaria 1041, Kaduna State, Nigeria
2
Lisboa School of Economics and Management, University of Lisbon, Rua Miguel Lupi, 1249-078 Lisboa, Portugal
*
Authors to whom correspondence should be addressed.
Future Internet 2025, 17(12), 549; https://doi.org/10.3390/fi17120549 (registering DOI)
Submission received: 16 September 2025 / Revised: 2 November 2025 / Accepted: 4 November 2025 / Published: 29 November 2025

Abstract

The Internet of Things (IoT) has influenced the healthcare industry by enabling real-time monitoring, data-driven decision-making, and automation of medical activities. IoT in healthcare comprises a network of interconnected medical devices, sensors, and software systems that gather, analyse, and transmit patient data, enhancing the efficiency, accuracy, and accessibility of healthcare services. Despite its benefits, the deployment and impact of IoT in healthcare vary between countries due to differences in healthcare infrastructure, regulatory frameworks, and technical advancements. This review highlights how IoT technologies underpin the efficiency of EHR and HIE systems by enabling continuous data flow, interoperability, and real-time patient care. It also addresses the problems involved with IoT adoption, including data privacy concerns, interoperability issues, high implementation costs, and cybersecurity dangers. Additionally, the paper examines future trends in IoT healthcare, including 5G integration, AI-enhanced healthcare analytics, blockchain-based security solutions, and the creation of energy-efficient IoT medical equipment. Through an analysis of worldwide trends and obstacles, this research offers suggestions for policies, methods, and best practices to close the digital healthcare gap and make sure that healthcare solutions powered by the IoT are available, safe, and effective everywhere.
Keywords: IoT; healthcare IoT (HIoT); smart hospitals; telemedicine; remote patient monitoring (RPM); AI- health information exchange (HIE) IoT; healthcare IoT (HIoT); smart hospitals; telemedicine; remote patient monitoring (RPM); AI- health information exchange (HIE)

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MDPI and ACS Style

Alaba, F.A.; Rocha, A.; Sulaimon, H.A.; Najeem, O. IoT Applications and Challenges in Global Healthcare Systems: A Comprehensive Review. Future Internet 2025, 17, 549. https://doi.org/10.3390/fi17120549

AMA Style

Alaba FA, Rocha A, Sulaimon HA, Najeem O. IoT Applications and Challenges in Global Healthcare Systems: A Comprehensive Review. Future Internet. 2025; 17(12):549. https://doi.org/10.3390/fi17120549

Chicago/Turabian Style

Alaba, Fadele Ayotunde, Alvaro Rocha, Hakeem Adewale Sulaimon, and Owamoyo Najeem. 2025. "IoT Applications and Challenges in Global Healthcare Systems: A Comprehensive Review" Future Internet 17, no. 12: 549. https://doi.org/10.3390/fi17120549

APA Style

Alaba, F. A., Rocha, A., Sulaimon, H. A., & Najeem, O. (2025). IoT Applications and Challenges in Global Healthcare Systems: A Comprehensive Review. Future Internet, 17(12), 549. https://doi.org/10.3390/fi17120549

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