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Open AccessEditorial

Antifungal and Antiparasitic Drug Delivery

1
Departament of Pharmaceutics and Food Technology, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain
2
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili and Institut d’Investigació Sanitària Pere Virgili (IISPV), 43201 Reus, Spain
*
Authors to whom correspondence should be addressed.
Pharmaceutics 2020, 12(4), 324; https://doi.org/10.3390/pharmaceutics12040324
Received: 25 March 2020 / Accepted: 1 April 2020 / Published: 4 April 2020
(This article belongs to the Special Issue Antifungal and Antiparasitic Drug Delivery)
Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”. View Full-Text
Keywords: liposomes; transferosomes; nanoparticles; emulsions; candidiasis; aspergillosis; azoles; amphotericin B; combined therapy; quality by design; leishmaniasis; malaria; trypanosomiasis liposomes; transferosomes; nanoparticles; emulsions; candidiasis; aspergillosis; azoles; amphotericin B; combined therapy; quality by design; leishmaniasis; malaria; trypanosomiasis
MDPI and ACS Style

Torrado, J.J.; Serrano, D.R.; Capilla, J. Antifungal and Antiparasitic Drug Delivery. Pharmaceutics 2020, 12, 324.

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