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Progress on the Prevention and Treatment of Hantavirus Disease

Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA
Author to whom correspondence should be addressed.
Viruses 2019, 11(7), 610;
Received: 1 June 2019 / Revised: 28 June 2019 / Accepted: 29 June 2019 / Published: 4 July 2019
(This article belongs to the Special Issue Hantaviruses)
PDF [230 KB, uploaded 4 July 2019]


Hantaviruses, members of the order Bunyavirales, family Hantaviridae, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year. The spectrum of disease associated with hantavirus infection include hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). There are currently no FDA-approved vaccines or treatments for these hantavirus diseases. This review provides a summary of the status of vaccine and antiviral treatment efforts including those tested in animal models or human clinical trials. View Full-Text
Keywords: hantavirus; hemorrhagic fever with renal syndrome; hantavirus pulmonary syndrome; vaccine; antiviral hantavirus; hemorrhagic fever with renal syndrome; hantavirus pulmonary syndrome; vaccine; antiviral
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Brocato, R.L.; Hooper, J.W. Progress on the Prevention and Treatment of Hantavirus Disease. Viruses 2019, 11, 610.

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