Next Article in Journal
Expanding the Diversity of Myoviridae Phages Infecting Lactobacillus plantarum—A Novel Lineage of Lactobacillus Phages Comprising Five New Members
Next Article in Special Issue
Complex History of Codiversification and Host Switching of a Newfound Soricid-Borne Orthohantavirus in North America
Previous Article in Journal
Conserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors
Previous Article in Special Issue
Cytokine Storm Combined with Humoral Immune Response Defect in Fatal Hemorrhagic Fever with Renal Syndrome Case, Tatarstan, Russia
Article Menu

Export Article

Open AccessReview

Progress on the Prevention and Treatment of Hantavirus Disease

Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA
*
Author to whom correspondence should be addressed.
Viruses 2019, 11(7), 610; https://doi.org/10.3390/v11070610
Received: 1 June 2019 / Revised: 28 June 2019 / Accepted: 29 June 2019 / Published: 4 July 2019
(This article belongs to the Special Issue Hantaviruses)
  |  
PDF [230 KB, uploaded 4 July 2019]

Abstract

Hantaviruses, members of the order Bunyavirales, family Hantaviridae, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year. The spectrum of disease associated with hantavirus infection include hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). There are currently no FDA-approved vaccines or treatments for these hantavirus diseases. This review provides a summary of the status of vaccine and antiviral treatment efforts including those tested in animal models or human clinical trials. View Full-Text
Keywords: hantavirus; hemorrhagic fever with renal syndrome; hantavirus pulmonary syndrome; vaccine; antiviral hantavirus; hemorrhagic fever with renal syndrome; hantavirus pulmonary syndrome; vaccine; antiviral
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Brocato, R.L.; Hooper, J.W. Progress on the Prevention and Treatment of Hantavirus Disease. Viruses 2019, 11, 610.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top