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The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland

Virology Unit, The Irish Equine Centre, Johnstown, Naas, Co. Kildare W91 RH93, Ireland
Equine Research Institute, Japan Racing Association, Shimotsuke, Tochigi 329-0412, Japan
Troytown Grey Abbey Equine Hospital, Green Road, Co. Kildare R51 YV04, Ireland
Author to whom correspondence should be addressed.
Viruses 2019, 11(10), 946;
Received: 27 July 2019 / Revised: 10 October 2019 / Accepted: 12 October 2019 / Published: 14 October 2019
(This article belongs to the Special Issue Equine Viruses)
The objective of this study was to investigate the presence of equine coronavirus (ECoV) in clinical samples submitted to a diagnostic laboratory in Ireland. A total of 424 clinical samples were examined from equids with enteric disease in 24 Irish counties between 2011 and 2015. A real-time reverse transcription polymerase chain reaction was used to detect ECoV RNA. Nucleocapsid, spike and the region from the p4.7 to p12.7 genes of positive samples were sequenced, and sequence and phylogenetic analyses were conducted. Five samples (1.2%) collected in 2011 and 2013 tested positive for ECoV. Positive samples were collected from adult horses, Thoroughbred foals and a donkey foal. Sequence and/or phylogenetic analysis showed that nucleocapsid, spike and p12.7 genes were highly conserved and were closely related to ECoVs identified in other countries. In contrast, the region from p4.7 and the non-coding region following the p4.7 gene had deletions or insertions. The differences in the p4.7 region between the Irish ECoVs and other ECoVs indicated that the Irish viruses were distinguishable from those circulating in other countries. This is the first report of ECoV detected in both foals and adult horses in Ireland. View Full-Text
Keywords: equine coronavirus; Ireland; enteric disease equine coronavirus; Ireland; enteric disease
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MDPI and ACS Style

Nemoto, M.; Schofield, W.; Cullinane, A. The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland. Viruses 2019, 11, 946.

AMA Style

Nemoto M, Schofield W, Cullinane A. The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland. Viruses. 2019; 11(10):946.

Chicago/Turabian Style

Nemoto, Manabu, Warren Schofield, and Ann Cullinane. 2019. "The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland" Viruses 11, no. 10: 946.

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