Structural Insights in Multifunctional Papillomavirus Oncoproteins
AbstractSince their discovery in the mid-eighties, the main papillomavirus oncoproteins E6 and E7 have been recalcitrant to high-resolution structure analysis. However, in the last decade a wealth of three-dimensional information has been gained on both proteins whether free or complexed to host target proteins. Here, we first summarize the diverse activities of these small multifunctional oncoproteins. Next, we review the available structural data and the new insights they provide about the evolution of E6 and E7, their multiple interactions and their functional variability across human papillomavirus (HPV) species. View Full-Text
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Suarez, I.; Trave, G. Structural Insights in Multifunctional Papillomavirus Oncoproteins. Viruses 2018, 10, 37.
Suarez I, Trave G. Structural Insights in Multifunctional Papillomavirus Oncoproteins. Viruses. 2018; 10(1):37.Chicago/Turabian Style
Suarez, Irina; Trave, Gilles. 2018. "Structural Insights in Multifunctional Papillomavirus Oncoproteins." Viruses 10, no. 1: 37.
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