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Shape-Memory Polymers in Dentistry: Systematic Review and Patent Landscape Report

Department of Surgical Sciences, CIR Dental School, Università degli Studi di Torino, Via Nizza, 230, 10126 Turin, Italy
Department of Mechanical and Aerospatial Engineering (DIMEAS), Politecnico di Torino, Duca degli Abruzzi, 24, 10129 Turin, Italy
Author to whom correspondence should be addressed.
Materials 2019, 12(14), 2216;
Received: 11 June 2019 / Revised: 29 June 2019 / Accepted: 8 July 2019 / Published: 10 July 2019
(This article belongs to the Special Issue Current and Future Trends in Dental Materials)
PDF [888 KB, uploaded 15 July 2019]


Objective: To perform a systematic review (SR) of existing literature and a patent landscape report (PLR) regarding the potential applications of shape-memory polymers (SMPs) in dentistry. Search strategy: Clinical and Biomedical online databases (Pubmed, Medline via Embase, Scopus, LILACS, Web of Science, Cochrane Library), Materials Science and Engineering databases (IEEE Explore, Compendex, Proquest), Material Science and Chemical database (Reaxys) so as Patents databases (Questel-Orbit, Espacenet, Patentscope) were consulted as recently as January 2019 to identify all papers and patents potentially relevant to the review. The reference lists of all eligible studies were hand searched for additional published work. Results: After duplicate selection and extraction procedures, 6 relevant full-text articles from the initial 302 and 45 relevant patents from 497 were selected. A modified Consolidated Standards of Reporting Trials (CONSORT) checklist of 14 items for reporting pre-clinical in-vitro studies was used to rate the methodological quality of the selected papers. The overall quality was judged low. Conclusions: Despite the great potential and versatility of SMPs, it was not possible to draw evidence-based conclusions supporting their immediate employment in clinical dentistry. This was due to the weak design and a limited number of studies included within this review and reflects the fact that additional research is mandatory to determine whether or not the use of SMPs in dentistry could be effective. Nevertheless, the qualitative analysis of selected papers and patents indicate that SMPs are promising materials in dentistry because of their programmable physical properties. These findings suggest the importance of furtherly pursuing this line of research. View Full-Text
Keywords: smart materials; stimuli responsive materials; shape memory polymers; dentistry; review; patent landscape report smart materials; stimuli responsive materials; shape memory polymers; dentistry; review; patent landscape report

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Bruni, A.; Serra, F.G.; Deregibus, A.; Castroflorio, T. Shape-Memory Polymers in Dentistry: Systematic Review and Patent Landscape Report. Materials 2019, 12, 2216.

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