Next Article in Journal
Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review
Next Article in Special Issue
Optical Aggregation of Gold Nanoparticles for SERS Detection of Proteins and Toxins in Liquid Environment: Towards Ultrasensitive and Selective Detection
Previous Article in Journal
Fe3O4 Nanoparticles in Targeted Drug/Gene Delivery Systems
Previous Article in Special Issue
Optimization and Characterization of Paper-Made Surface Enhanced Raman Scattering (SERS) Substrates with Au and Ag NPs for Quantitative Analysis
Open AccessFeature PaperArticle

TopUp SERS Substrates with Integrated Internal Standard

1
Leibniz Institute of Photonic Technology e. V. (IPHT), Albert-Einstein-Str. 9, 07745 Jena, Germany
2
Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller-University Jena, Helmholtzweg 4, 07743 Jena, Germany
*
Authors to whom correspondence should be addressed.
Materials 2018, 11(2), 325; https://doi.org/10.3390/ma11020325
Received: 11 December 2017 / Revised: 12 February 2018 / Accepted: 20 February 2018 / Published: 24 February 2018
(This article belongs to the Special Issue SERS-Active Substrates)
Surface-enhanced Raman spectroscopy (SERS) is known as a molecular-specific and highly sensitive method. In order to enable the routine application of SERS, powerful SERS substrates are of great importance. Within this manuscript, a TopUp SERS substrate is introduced which is fabricated by a top-down process based on microstructuring as well as a bottom-up generation of silver nanostructures. The Raman signal of the support material acts as an internal standard in order to improve the quantification capabilities. The analyte molecule coverage of sulfamethoxazole on the surface of the nanostructures is characterized by the SERS signal evolution fitted by a Langmuir–Freundlich isotherm. View Full-Text
Keywords: SERS; TopUp SERS substrate; sulfamethoxazole; Langmuir–Freundlich isotherm SERS; TopUp SERS substrate; sulfamethoxazole; Langmuir–Freundlich isotherm
Show Figures

Figure 1

MDPI and ACS Style

Patze, S.; Huebner, U.; Weber, K.; Cialla-May, D.; Popp, J. TopUp SERS Substrates with Integrated Internal Standard. Materials 2018, 11, 325.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop