Next Article in Journal
Methodology for the Assessment of the Ecotoxicological Potential of Construction Materials
Next Article in Special Issue
Molybdenum Dichalcogenides for Environmental Chemical Sensing
Previous Article in Journal
Understanding Drug Release Data through Thermodynamic Analysis
Previous Article in Special Issue
Solid-State Method Synthesis of SnO2-Decorated g-C3N4 Nanocomposites with Enhanced Gas-Sensing Property to Ethanol
Open AccessArticle

Synthesis of Au [email protected]2 Quantum Dots [email protected] Nanocomposites for SERS Bio-Analysis and Label-Free Bio-Imaging

MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou 510631, Guangdong, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Elisabetta Comini
Materials 2017, 10(6), 650; https://doi.org/10.3390/ma10060650
Received: 13 April 2017 / Revised: 11 May 2017 / Accepted: 26 May 2017 / Published: 13 June 2017
(This article belongs to the Special Issue Ultrathin Two-dimensional (2D) Nanomaterials)
In this work, we report a facile method using MoS2 quantum dots (QDs) as reducers to directly react with HAuCl4 for the synthesis of Au [email protected]2 quantum dots (Au [email protected]2 QDs) [email protected] nanocomposites with an ultrathin shell of ca. 1 nm. The prepared Au [email protected]2 QDs reveal high surface enhanced Raman scattering (SERS) performance regarding sensitivity as well as the satisfactory SERS reproducibility and stability. The limit of detection of the hybrids for crystal violet can reach 0.5 nM with a reasonable linear response range from 0.5 μM to 0.5 nM (R2 ≈ 0.974). Furthermore, the near-infrared SERS detection based on Au [email protected]2 QDs in living cells is achieved with distinct Raman signals which are clearly assigned to the various cellular components. Meanwhile, the distinguishable SERS images are acquired from the 4T1 cells with the incubation of Au [email protected]2 QDs. Consequently, the straightforward strategy of using Au [email protected]2 QDs exhibits great potential as a superior SERS substrate for chemical and biological detection as well as bio-imaging. View Full-Text
Keywords: MoS2 quantum dots; Au nanoparticles; surface enhanced Raman scattering; tumor cells MoS2 quantum dots; Au nanoparticles; surface enhanced Raman scattering; tumor cells
Show Figures

Figure 1

MDPI and ACS Style

Fei, X.; Liu, Z.; Hou, Y.; Li, Y.; Yang, G.; Su, C.; Wang, Z.; Zhong, H.; Zhuang, Z.; Guo, Z. Synthesis of Au [email protected]2 Quantum Dots [email protected] Nanocomposites for SERS Bio-Analysis and Label-Free Bio-Imaging. Materials 2017, 10, 650.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop