Open AccessArticle
Catheter Ablation for Atrial Fibrillation in a Real-World Setting
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Laurent M. Haegeli, Fabian Jud, Chol Jun On, Christine Gstrein, Ardan M. Saguner, Jan Steffel, Stefano Benussi, Nazmi Krasniqi, Corinna Brunckhorst, Thomas F. Lüscher, Thomas Wolber and Firat Duru
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Abstract
Introduction: Several prospective multi-center randomized trials have established the efficacy of catheter ablation in patients with atrial fibrillation (AF). The aim of this study was to assess the mid-term results after AF ablation in a real-world cohort in a single tertiary care
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Introduction: Several prospective multi-center randomized trials have established the efficacy of catheter ablation in patients with atrial fibrillation (AF). The aim of this study was to assess the mid-term results after AF ablation in a real-world cohort in a single tertiary care center in Switzerland.
Methods: This prospective registry comprised all patients with paroxysmal or persistent AF undergoing a catheter ablation procedure at the University Heart Center Zurich between June 2009 and April 2013 with a clinical follow-up including symptom assessment and long-term ECG monitoring for at least 24 hours.
Results: A total of 275 consecutive ablation procedures were performed in 201 patients (mean age 62 ± 9 years, 75% men). Patients had paroxysmal AF in 62% and persistent in 38%. Left ventricular ejection fraction as assessed by transthoracic echocardiogram was 58 ± 8%, the diameter of the left atrium averaged 44 ± 7 mm. Hypertension was present in 49%, coronary artery disease in 13% of patients. Pericardial tamponade occurred in 3% of the procedures. No other major complication requiring interventions or cardiac surgery was observed. After a follow-up period of 19.1 ± 11.8 months, 84% of the patients had a significant (>90%) reduction of their arrhythmia burden. Freedom from AF was observed in 73% of all patients.
Conclusion: In our cohort sinus rhythm was maintained in the majority of patients who underwent catheter ablation for paroxysmal or persistent AF after a mid-term follow-up with a very low periprocedural complication rate.
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