Next Article in Journal
Development and Validation of an HPLC Method for the Quantitative Analysis of Bromophenolic Compounds in the Red Alga Vertebrata lanosa
Next Article in Special Issue
Alginate Oligosaccharides Affect Mechanical Properties and Antifungal Activity of Alginate Buccal Films with Posaconazole
Previous Article in Journal
Astaxanthin Suppresses Cigarette Smoke-Induced Emphysema through Nrf2 Activation in Mice
Previous Article in Special Issue
Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms
Open AccessReview

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

by Qiwu Zhong 1,†, Bin Wei 1,†, Sijia Wang 1,2, Songze Ke 1, Jianwei Chen 1, Huawei Zhang 1 and Hong Wang 1,*
1
College of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China
2
Center for Human Nutrition, David Geffen School of Medicine, University of California, Rehabilitation Building 32-21, 1000 Veteran Avenue, Los Angeles, CA 90024, USA
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Mar. Drugs 2019, 17(12), 674; https://doi.org/10.3390/md17120674
Received: 12 October 2019 / Revised: 14 November 2019 / Accepted: 22 November 2019 / Published: 29 November 2019
(This article belongs to the Special Issue Marine Polysaccharides in Pharmaceutical Applications)
Marine-derived antioxidant polysaccharides have aroused extensive attention because of their potential nutritional and therapeutic benefits. However, the comprehensive comparison of identified marine-derived antioxidant polysaccharides is still inaccessible, which would facilitate the discovery of more efficient antioxidants from marine organisms. Thus, this review summarizes the sources, chemical composition, structural characteristics, and antioxidant capacity of marine antioxidant polysaccharides, as well as their protective in vivo effects mediated by antioxidative stress reported in the last few years (2013–2019), and especially highlights the dominant role of marine algae as antioxidant polysaccharide source. In addition, the relationships between the chemical composition and structural characteristics of marine antioxidant polysaccharides with their antioxidant capacity were also discussed. The antioxidant activity was found to be determined by multiple factors, including molecular weight, monosaccharide composition, sulfate position and its degree. View Full-Text
Keywords: antioxidant activity; marine organisms; polysaccharides; chemical composition; structural characteristics; structure–activity relationship antioxidant activity; marine organisms; polysaccharides; chemical composition; structural characteristics; structure–activity relationship
Show Figures

Graphical abstract

MDPI and ACS Style

Zhong, Q.; Wei, B.; Wang, S.; Ke, S.; Chen, J.; Zhang, H.; Wang, H. The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview. Mar. Drugs 2019, 17, 674.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop