Next Article in Journal
Epilepsy in Paediatric Palliative Care: Prevalence, Clinical Correlations and the Development of a Consensus-Based Seizure Management Protocol
Previous Article in Journal
The Effect of Pediatric Liver Transplantation on Depression Levels in Children and the Potential Role of Liver Enzymes as Biomarkers
Previous Article in Special Issue
Clinical and Psychological Impact of COVID-19 on Maintenance Hemodialysis Patients: Hospitalization Burden, De Novo Anxiolytic Use, and Long-Term Survival
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID): Scale Development and Validation

1
Center for Applied Neuroscience, University of Cyprus, Nicosia 1678, Cyprus
2
Department of Psychology, University of Cyprus, Nicosia 1678, Cyprus
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Medicina 2026, 62(6), 1149; https://doi.org/10.3390/medicina62061149 (registering DOI)
Submission received: 28 April 2026 / Revised: 21 May 2026 / Accepted: 4 June 2026 / Published: 12 June 2026
(This article belongs to the Special Issue The Burden of COVID-19 Pandemic on Mental Health, 2nd Edition)

Abstract

Background and Objectives: The neurocognitive sequelae of COVID-19 have attracted attention as part of post-COVID condition (PCC), yet standardized tools for screening and quantifying PCC-related cognitive impairment remain scarce. The present study aimed to develop and validate the Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID), a self-report questionnaire designed to capture current symptom burden and perceived changes in cognitive functioning relative to pre-COVID status in a Greek-speaking sample. Materials and Methods: Data collection occurred in three phases between August 2024 and February 2025. Dataset A (N = 27) was used for test–retest reliability. Dataset B (N = 300) was used for exploratory factor analysis (EFA), reliability testing, and convergent validity analyses with the Brain Fog Scale (BFS). Dataset C (N = 317) was used for independent validation through confirmatory factor analysis (CFA). Results: Initial EFA of the 30-item SNAP-COVID scale suggested a four-factor model, yet further item refinement yielded a robust three-factor, 24-item solution: (1) General Cognitive Functions (17 items, α = 0.948), (2) Sensory Hypersensitivity (4 items, α = 0.829), and (3) Language and Communication (3 items, α = 0.950). The total scale demonstrated excellent internal consistency (α = 0.95). Convergent validity was evident by significant correlations between SNAP impact scores and BFS scores (r = −0.442, p < 0.001). CFA confirmed the three-factor structure with acceptable fit indices (χ2(249) = 677.29, p < 0.001; CFI = 0.882; TLI = 0.869; RMSEA = 0.074; SRMR = 0.032). Conclusions: The SNAP-COVID scale is a reliable and valid instrument. Its multidimensional structure captures global and domain-specific difficulties, addressing a critical gap in post-infectious cognitive assessment.
Keywords: post-COVID condition; cognitive impairment; scale development; psychometric validation post-COVID condition; cognitive impairment; scale development; psychometric validation

Share and Cite

MDPI and ACS Style

Nikolaou, F.; Solomou, I.; Loizidou, M.; Papettas, P.; Giorgoudi, E.; Lofitou, K.; Constantinidou, F. Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID): Scale Development and Validation. Medicina 2026, 62, 1149. https://doi.org/10.3390/medicina62061149

AMA Style

Nikolaou F, Solomou I, Loizidou M, Papettas P, Giorgoudi E, Lofitou K, Constantinidou F. Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID): Scale Development and Validation. Medicina. 2026; 62(6):1149. https://doi.org/10.3390/medicina62061149

Chicago/Turabian Style

Nikolaou, Flora, Ioulia Solomou, Maria Loizidou, Panagiotis Papettas, Eleni Giorgoudi, Kalia Lofitou, and Fofi Constantinidou. 2026. "Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID): Scale Development and Validation" Medicina 62, no. 6: 1149. https://doi.org/10.3390/medicina62061149

APA Style

Nikolaou, F., Solomou, I., Loizidou, M., Papettas, P., Giorgoudi, E., Lofitou, K., & Constantinidou, F. (2026). Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID): Scale Development and Validation. Medicina, 62(6), 1149. https://doi.org/10.3390/medicina62061149

Article Metrics

Back to TopTop