Frequency and Age-Related Changes in Corneal Astigmatism in Cataract Surgery Candidates at a Training Hospital in Turkey
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Examination Procedure and Data Collection
2.3. Definitions
2.4. Statistical Analysis
2.5. Test–Retest Reliability for Keratometric Measurements
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Narang, R.; Agarwal, A. Refractive cataract surgery. Curr. Opin. Ophthalmol. 2024, 35, 23–27. [Google Scholar] [PubMed]
- Park, R.B.; Aref, A.A. Astigmatism Management in Modern Cataract Surgery. Vision 2024, 8, 9. [Google Scholar] [CrossRef]
- Shoaib, K.K.; Shakoor, T. Corneal Astigmatism in Cataract. J. Coll. Physicians Surg. Pak. 2024, 34, 97–100. [Google Scholar] [CrossRef]
- Bian, L.; Ma, B.; Sun, Z.; Li, W.; Liu, Y.; Qin, R.; Chen, J.; Ma, Y.; Zhao, L.; Qi, H. Prevalence data for total corneal astigmatism in cataract patients. Graefes Arch. Clin. Exp. Ophthalmol. 2024, 262, 3219–3227. [Google Scholar] [PubMed]
- Zhang, J.; Wu, Y.; Sharma, B.; Gupta, R.; Jawla, S.; Bullimore, M.A. Epidemiology and Burden of Astigmatism: A Systematic Literature Review. Optom. Vis. Sci. 2023, 100, 218–231. [Google Scholar] [CrossRef]
- Hashemian, S.J.; Hashemian, S.M.; Karimian, F.; Hadavandkhani, A.; Jafari, M.E.; Hashemian, M.S.; Hadi, Y.; Semnani, F.N. Ocular Biometric Values and Prevalence of Corneal Astigmatism in Patients Candidate for Cataract Surgery. J. Curr. Ophthalmol. 2022, 34, 56–59. [Google Scholar] [CrossRef] [PubMed]
- Arriola-Villalobos, P.; Burgos-Blasco, B.; Fernández-Vigo, J.I.; Ariño-Gutiérrez, M.; Burgos-Blasco, P.; Carmona-González, D.; Fernández-Pérez, C. Biometry data and prevalence of corneal astigmatism in caucasian spanish candidates for cataract surgery. J. Fr. Ophtalmol. 2021, 44, 76–83. [Google Scholar] [CrossRef]
- Abu-Ain, M.S.; Al-Latayfeh, M.M.; Khan, M.I. Do limbal relaxing incisions during cataract surgery still have a role? BMC Ophthalmol. 2022, 22, 102. [Google Scholar] [CrossRef]
- Gupta, S.; Kalra, N.; Singh, A.; Mishra, A.; Kaushik, J. A prospective study to compare the safety and efficacy of toric intra-ocular lens vs. opposite clear corneal incision in patients undergoing phacoemulsification for age-related cataract with pre-existing corneal astigmatism. Rom. J. Ophthalmol. 2025, 69, 74–82. [Google Scholar]
- Jiang, Z.; Zhang, N.; Zhu, M.; Huang, L.; Dong, J. Effects of toric intraocular lens in cataract patients with axial myopia and regular corneal astigmatism at primary hospitals. Int. Ophthalmol. 2025, 45, 172. [Google Scholar] [CrossRef]
- Ning, R.; Xu, H.; Li, Z.; Yu, J.; Xu, S.; Lei, C.S.; Wang, Y.; Savini, G.; Schiano-Lomoriello, D.; Zhou, X.; et al. Agreement between a new fully automatic ocular biometer based on optical low-coherence reflectometry and an optical biometer based on Scheimpflug imaging combined with partial coherence interferometry. BMC Ophthalmol. 2024, 24, 455. [Google Scholar] [CrossRef]
- Kanclerz, P.; Hecht, I.; Tuuminen, R. Technical failure rates for biometry between swept-source and older-generation optical coherence methods: A review and meta-analysis. BMC Ophthalmol. 2023, 23, 182. [Google Scholar] [CrossRef] [PubMed]
- Vats, S.; Kumari, L.; Goenka, R.; Agrawal, M.; Mishra, S. Pattern of astigmatism using partial coherence interferometry in patients of different age groups undergoing cataract surgery. Oman J. Ophthalmol. 2022, 15, 295–298. [Google Scholar] [CrossRef] [PubMed]
- Wu, Z.; Liu, C.; Chen, Z. Prevalence and Age-Related Changes of Corneal Astigmatism in Patients Undergoing Cataract Surgery in Northern China. J. Ophthalmol. 2020, 2020, 6385098. [Google Scholar] [CrossRef]
- Joshi, R.S.; Jadhav, S.A. Frequency of Corneal Astigmatism in Patients Presenting for Senile Cataract Surgery at a Teaching Hospital in Indian Rural Population. Asia Pac. J. Ophthalmol. 2020, 9, 126–129. [Google Scholar] [CrossRef] [PubMed]
- Thibos, L.N.; Wheeler, W.; Horner, D. Power vectors: An application of Fourier analysis to the description and statistical analysis of refractive error. Optom. Vis. Sci. 1997, 74, 367–375. [Google Scholar] [CrossRef]
- Guan, Z.; Yuan, F.; Yuan, Y.-Z.; Niu, W.-R. Analysis of corneal astigmatism in cataract surgery candidates at a teaching hospital in Shanghai, China. J. Cataract Refract. Surg. 2012, 38, 1970–1977. [Google Scholar] [CrossRef]
- Hayashi, K.; Sato, T.; Sasaki, H.; Hirata, A.; Yoshimura, K. Sex-related differences in corneal astigmatism and shape with age. J. Cataract Refract. Surg. 2018, 44, 1130–1139. [Google Scholar] [CrossRef]
- Hasegawa, Y.; Honbo, M.; Miyata, K.; Oshika, T. Type of residual astigmatism and uncorrected visual acuity in pseudophakic eyes. Sci. Rep. 2022, 12, 1225. [Google Scholar] [CrossRef]
- Yoon, Y.C.; Ha, M.; Whang, W.J. Comparison of surgically induced astigmatism between anterior and total cornea in 2.2 mm steep meridian incision cataract surgery. BMC Ophthalmol. 2021, 21, 373. [Google Scholar] [CrossRef]
- Langenbucher, A.; Szentmáry, N.; Cayless, A.; Casaza, M.; Weisensee, J.; Hoffmann, P.; Wendelstein, J. Surgically Induced Astigmatism after Cataract Surgery—A Vector Analysis. Curr. Eye Res. 2022, 47, 1279–1287. [Google Scholar] [CrossRef]
- Oh, E.H.; Kim, H.; Lee, H.S.; Hwang, K.Y.; Joo, C.K. Analysis of anterior corneal astigmatism before cataract surgery using power vector analysis in eyes of Korean patients. J. Cataract Refract. Surg. 2015, 41, 1256–1263. [Google Scholar] [CrossRef]
- Sharma, A.; Phulke, S.; Agrawal, A.; Kapoor, I.; Bansal, R.K. Prevalence of Astigmatism in Patients Undergoing Cataract Surgery at a Tertiary Care Center in North India. Clin. Ophthalmol. 2021, 15, 617–622. [Google Scholar] [CrossRef] [PubMed]
- Chen, W.; Zuo, C.; Chen, C.; Su, J.; Luo, L.; Congdon, N.; Liu, Y. Prevalence of corneal astigmatism before cataract surgery in Chinese patients. J. Cataract Refract. Surg. 2013, 39, 188–192. [Google Scholar] [CrossRef]
- Duman, R.; Duman, R.; Cetinkaya, E.; Sabaner, M.C.; Inan, S.; Doğan, M.; Doğan, İ. Analysis of corneal astigmatism with NIDEK axial length scan in caucasian cataract surgery candidates. Niger. J. Clin. Pract. 2018, 21, 456–461. [Google Scholar] [CrossRef] [PubMed]
- Guven, S. Comparison of corneal astigmatism characteristics and prevalence of corneal astigmatism between Turkish individuals and Syrian refugees. Eur. J. Ophthalmol. 2022, 32, 1504–1512. [Google Scholar] [CrossRef] [PubMed]
- McAlinden, C.; Janicek, D. Toric Intraocular Lenses for the Management of Corneal Astigmatism at the Time of Cataract Surgery. J. Ophthalmol. 2021, 2021, 3286043. [Google Scholar] [CrossRef]
- Singh, A.; Kapoor, G.; Baranwal, V.K.; Kalra, N. Rotational stability of Toric intraocular lenses. Med. J. Armed Forces India 2022, 78, 68–73. [Google Scholar] [CrossRef]
- Hoffmann, P.C.; Hutz, W.W. Analysis of biometry and prevalence data for corneal astigmatism in 23,239 eyes. J. Cataract Refract. Surg. 2010, 36, 1479–1485. [Google Scholar] [CrossRef]
- Yuan, X.; Song, H.; Peng, G.; Hua, X.; Tang, X. Prevalence of corneal astigmatism in patients before cataract surgery in Northern China. J. Ophthalmol. 2014, 2014, 536412. [Google Scholar] [CrossRef]
- Raúl, L.E.; Milena, O.A.; Alberto, V.L.; Emilio, C.A. Corneal astigmatism in cataract surgery candidates. Rev. Bras. Oftalmol. 2018, 77, 272–277. [Google Scholar]
- De Bernardo, M.; Zeppa, L.; Cennamo, M.; Iaccarino, S.; Zeppa, L.; Rosa, N. Prevalence of corneal astigmatism before cataract surgery in Caucasian patients. Eur. J. Ophthalmol. 2014, 24, 494–500. [Google Scholar] [CrossRef] [PubMed]
- Isyaku, M.; Ali, S.A.; Hassan, S. Preoperative corneal astigmatism among adult patients with cataract in Northern Nigeria. Indian J. Ophthalmol. 2014, 62, 1094–1095. [Google Scholar] [CrossRef]
- Prasher, P.; Sandhu, J.S. Prevalence of corneal astigmatism before cataract surgery in Indian population. Int. Ophthalmol. 2017, 37, 683–689. [Google Scholar] [CrossRef]
- Lekhanont, K.; Wuthisiri, W.; Chatchaipun, P.; Vongthongsri, A. Prevalence of corneal astigmatism in cataract surgery candidates in Bangkok, Thailand. J. Cataract Refract. Surg. 2011, 37, 613–615. [Google Scholar] [CrossRef] [PubMed]
- Michelitsch, M.; Ardjomand, N.; Vidic, B.; Wedrich, A.; Steinwender, G. Prevalence and age-related changes of corneal astigmatism in patients before cataract surgery. Ophthalmologe 2017, 114, 247–251. [Google Scholar] [CrossRef]
- Liu, Y.C.; Chou, P.; Wojciechowski, R.; Lin, P.Y.; Liu, C.J.; Chen, S.J.; Liu, J.-H.; Hsu, W.-M.; Cheng, C.-Y. Power vector analysis of refractive, corneal, and internal astigmatism in an elderly Chinese population: The Shihpai Eye Study. Investig. Ophthalmol. Vis. Sci. 2011, 52, 9651–9657. [Google Scholar] [CrossRef]
- Ferrer Blasco, T.; Montés Micó, R.; Peixoto de Matos, S.C.; González Méijome, J.M.; Cerviño, A. Prevalence of corneal astigmatism before cataract surgery. J. Cataract Refract. Surg. 2009, 35, 70–75. [Google Scholar] [CrossRef]
- Hayashi, K.; Manabe, S.I.; Hirata, A.; Yoshimura, K. Changes in corneal astigmatism during 20 years after cataract surgery. J. Cataract Refract. Surg. 2017, 43, 615–621. [Google Scholar] [CrossRef]
- Hayashi, K.; Hirata, A.; Manabe, S.; Hayashi, H. Long term change in corneal astigmatism after sutureless cataract surgery. Am. J. Ophthalmol. 2011, 151, 858–865. [Google Scholar] [CrossRef] [PubMed]
- Read, S.A.; Collins, M.J.; Carney, L.G. A review of astigmatism and its possible genesis. Clin. Exp. Optom. 2007, 90, 5–19. [Google Scholar] [CrossRef] [PubMed]
- Lyall, D.A.; Srinivasan, S.; Ng, J.; Kerr, E. Changes in corneal astigmatism among patients with visually significant cataract. Can. J. Ophthalmol. 2014, 49, 297–303. [Google Scholar] [CrossRef]
- Hayashi, K.; Yoshida, M.; Hayashi, S.; Hirata, A. Long-term changes in the refractive effect of a toric intraocular lens on astigmatism correction. Graefes Arch. Clin. Exp. Ophthalmol. 2022, 260, 509–519. [Google Scholar]
- Mohammadi, M.; Naderan, M.; Pahlevani, R.; Jahanrad, A. Prevalence of corneal astigmatism before cataract surgery. Int. Ophthalmol. 2016, 36, 807–817. [Google Scholar] [CrossRef]
- Riley, A.F.; Grupcheva, C.N.; Malik, T.Y.; Craig, J.P.; McGhee, C.N. The Auckland Cataract Study: Demographic, corneal topographic and ocular biometric parameters. Clin. Exp. Ophthalmol. 2001, 29, 381–386. [Google Scholar] [CrossRef] [PubMed]
- Langenbucher, A.; Cayless, A.; Szentmáry, N.; Weisensee, J.; Wendelstein, J.; Hoffmann, P. Prediction of total corneal power from measured anterior corneal power on the IOLMaster 700 using a feedforward shallow neural network. Acta Ophthalmol. 2022, 100, e1080–e1087. [Google Scholar] [CrossRef] [PubMed]
- Mohammadi, S.F.; Bu, S.; Jiang, Y.; Gao, Y.; Bai, X.; Chen, X.; Zhang, H.; Tian, F. The impact of posterior corneal astigmatism on the surgical planning of toric multifocal intraocular lens implantation. Adv. Ophthalmol. Pract. Res. 2022, 3, 39–46. [Google Scholar]




| Characteristics | Value |
|---|---|
| Total number of eyes (n) | 2152 |
| Age (years) | |
| Mean ± SD | 70.56 ± 8.88 |
| Range | 40 to 94 |
| Male, no. (%) | 1010 (46.9) |
| Corneal astigmatism (D) | |
| Mean ± SD | 0.96 ± 0.72 |
| Range | 0.00 to 8.31 |
| Mean ± SD (K1) | 43.32 ± 1.60 |
| Mean ± SD (K2) | 44.28 ± 1.66 |
| J0 (D) | |
| Mean ± SD | 0.05 ± 0.51 |
| Range | −2.29 to 4.38 |
| J45 (D) | |
| Mean ± SD | 0.01 ± 0.30 |
| Range | −1.96 to 1.95 |
| Axis of astigmatism, no. (%) | |
| With–the-rule | 934 (43.4) |
| Against-the-rule | 806 (37.5) |
| Oblique | 412 (19.1) |
| Axial length (mm) | 23.46 ± 1.02 |
| Anterior chamber depth (mm) | 3.08 ± 0.40 |
| IOL power (D) | 21.04 ± 2.47 |
| Toric IOL, no. (%) | 321 (14.9) |
| Corneal Astigmatism | Total | Age < 65 Years | Age ≥ 65 Years | |||
|---|---|---|---|---|---|---|
| r | p Value | r | p Value | r | p Value | |
| With-the-rule astigmatism | −0.056 | 0.088 | −0.217 * | <0.001 | 0.020 | 0.617 |
| Against-the-rule astigmatism | 0.148 * | <0.001 | −0.098 | 0.311 | 0.153 * | <0.001 |
| Oblique astigmatism | 0.098 | 0.078 | 0.047 | 0.653 | 0.077 | 0.171 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the authors. Published by MDPI on behalf of the Lithuanian University of Health Sciences. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Yilmaz, A.C.; Cakir Ince, B.A.; Ayyildiz, O.; Mutlu, F.M. Frequency and Age-Related Changes in Corneal Astigmatism in Cataract Surgery Candidates at a Training Hospital in Turkey. Medicina 2026, 62, 231. https://doi.org/10.3390/medicina62010231
Yilmaz AC, Cakir Ince BA, Ayyildiz O, Mutlu FM. Frequency and Age-Related Changes in Corneal Astigmatism in Cataract Surgery Candidates at a Training Hospital in Turkey. Medicina. 2026; 62(1):231. https://doi.org/10.3390/medicina62010231
Chicago/Turabian StyleYilmaz, Alper Can, Bagim Aycin Cakir Ince, Onder Ayyildiz, and Fatih Mehmet Mutlu. 2026. "Frequency and Age-Related Changes in Corneal Astigmatism in Cataract Surgery Candidates at a Training Hospital in Turkey" Medicina 62, no. 1: 231. https://doi.org/10.3390/medicina62010231
APA StyleYilmaz, A. C., Cakir Ince, B. A., Ayyildiz, O., & Mutlu, F. M. (2026). Frequency and Age-Related Changes in Corneal Astigmatism in Cataract Surgery Candidates at a Training Hospital in Turkey. Medicina, 62(1), 231. https://doi.org/10.3390/medicina62010231

