SDHx and Non-Chromaffin Tumors: A Mediastinal Germ Cell Tumor Occurring in a Young Man with Germline SDHB Mutation
Abstract
:1. Introduction
2. Case Presentation
3. Materials and Methods
3.1. Molecular Analysis
3.2. Loss of Heterozygosity (LOH) Analysis
3.3. Immunohistochemistry (IHC)
4. Results
5. Discussion
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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LH (nv 1.7–8.6 mUI/mL) | FSH (nv 1.5–12.4 mUI/mL) | Testosterone (nv 4.1–32.9 nmol/L) | β-hCG (nv 0.1–2 U/L) | |
---|---|---|---|---|
Before surgery | <0.3 | <0.3 | 32 | 35.4 |
After surgery | 7.4 | 5.1 | 22 | 0.1 |
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De Filpo, G.; Cilotti, A.; Rolli, L.; Pastorino, U.; Sonzogni, A.; Pradella, S.; Cantini, G.; Ercolino, T.; Nesi, G.; Mannelli, M.; et al. SDHx and Non-Chromaffin Tumors: A Mediastinal Germ Cell Tumor Occurring in a Young Man with Germline SDHB Mutation. Medicina 2020, 56, 561. https://doi.org/10.3390/medicina56110561
De Filpo G, Cilotti A, Rolli L, Pastorino U, Sonzogni A, Pradella S, Cantini G, Ercolino T, Nesi G, Mannelli M, et al. SDHx and Non-Chromaffin Tumors: A Mediastinal Germ Cell Tumor Occurring in a Young Man with Germline SDHB Mutation. Medicina. 2020; 56(11):561. https://doi.org/10.3390/medicina56110561
Chicago/Turabian StyleDe Filpo, Giuseppina, Antonio Cilotti, Luigi Rolli, Ugo Pastorino, Angelica Sonzogni, Silvia Pradella, Giulia Cantini, Tonino Ercolino, Gabriella Nesi, Massimo Mannelli, and et al. 2020. "SDHx and Non-Chromaffin Tumors: A Mediastinal Germ Cell Tumor Occurring in a Young Man with Germline SDHB Mutation" Medicina 56, no. 11: 561. https://doi.org/10.3390/medicina56110561