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Review

Diagnosis and Management of Left Atrium Appendage Thrombosis in Atrial Fibrillation Patients Undergoing Cardioversion

1
Department of Cardiology, AO dei Colli, Monaldi Hospital, 80131 Naples, Italy
2
Institute of Biostructure and Bioimaging, National Council Research, 80131 Naples, Italy
3
Anesthesiology and Intensive Care Unit, AO dei Colli, Monaldi Hospital, 80131 Naples, Italy
*
Author to whom correspondence should be addressed.
Medicina 2019, 55(9), 511; https://doi.org/10.3390/medicina55090511
Submission received: 25 June 2019 / Revised: 4 August 2019 / Accepted: 19 August 2019 / Published: 21 August 2019
(This article belongs to the Special Issue Stroke, Dementia and Atrial Fibrillation)

Abstract

Atrial fibrillation is the most common cardiac arrhythmia and is associated with an increased risk of stroke and thromboembolic complications. A rhythm control strategy with both electrical and pharmacological cardioversion is recommended for patients with symptomatic atrial fibrillation. Anticoagulant therapy for 3–4 weeks prior to cardioversion is recommended in order to avoid thromboembolic events deriving from restoring sinus rhythm. Transesophageal echocardiography has a pivotal role in this setting, excluding the presence of left atrial appendage thrombus before cardioversion. The aim of this review is to discuss the epidemiology and risk factors for left atrial appendage thrombosis, the role of echocardiography in the decision making before cardioversion, and the efficacy of different anticoagulant regimens on the detection and treatment of left atrial appendage thrombosis.
Keywords: atrial fibrillation; cardioversion; oral anticoagulation therapy; left atrial appendage thrombosis; transesophageal echocardiography atrial fibrillation; cardioversion; oral anticoagulation therapy; left atrial appendage thrombosis; transesophageal echocardiography

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MDPI and ACS Style

Melillo, E.; Palmiero, G.; Ferro, A.; Mocavero, P.E.; Monda, V.; Ascione, L. Diagnosis and Management of Left Atrium Appendage Thrombosis in Atrial Fibrillation Patients Undergoing Cardioversion. Medicina 2019, 55, 511. https://doi.org/10.3390/medicina55090511

AMA Style

Melillo E, Palmiero G, Ferro A, Mocavero PE, Monda V, Ascione L. Diagnosis and Management of Left Atrium Appendage Thrombosis in Atrial Fibrillation Patients Undergoing Cardioversion. Medicina. 2019; 55(9):511. https://doi.org/10.3390/medicina55090511

Chicago/Turabian Style

Melillo, Enrico, Giuseppe Palmiero, Adele Ferro, Paola Elvira Mocavero, Vittorio Monda, and Luigi Ascione. 2019. "Diagnosis and Management of Left Atrium Appendage Thrombosis in Atrial Fibrillation Patients Undergoing Cardioversion" Medicina 55, no. 9: 511. https://doi.org/10.3390/medicina55090511

APA Style

Melillo, E., Palmiero, G., Ferro, A., Mocavero, P. E., Monda, V., & Ascione, L. (2019). Diagnosis and Management of Left Atrium Appendage Thrombosis in Atrial Fibrillation Patients Undergoing Cardioversion. Medicina, 55(9), 511. https://doi.org/10.3390/medicina55090511

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