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Medicina, Volume 55, Issue 9

September 2019 - 101 articles

Cover Story: Obesity is considered to be a 20th-century pandemic, and its prevalence correlates with increasing global pollution. In our environment, we can identify chemical compounds that are able to influence the mechanisms responsible for energy homeostasis. These substances are called obesogens, and may contribute to the development of obesity directly by altering the pathways of food intake; influencing adipose tissue differentiation and metabolism; and, indirectly, by shifting the energy balance to favour calorie storage. Where can we find them and how can we avoid them? View this paper.
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Articles (101)

  • Article
  • Open Access
18 Citations
3,628 Views
11 Pages

Lung Cryobiopsy for the Diagnosis of Interstitial Lung Diseases: A Series Contribution to a Debated Procedure

  • Sergio Harari,
  • Francesca Cereda,
  • Federico Pane,
  • Alberto Cavazza,
  • Nikolaos Papanikolaou,
  • Giuseppe Pelosi,
  • Monica Scarioni,
  • Elisabetta Uslenghi,
  • Maurizio Zompatori and
  • Antonella Caminati

19 September 2019

Introduction: Transbronchial cryobiopsy is an alternative to surgical biopsy for the diagnosis of fibrosing interstitial lung diseases, although the role of this relatively new method is rather controversial. Aim of this study is to evaluate the diag...

  • Review
  • Open Access
8 Citations
3,663 Views
11 Pages

DNA Methylation and Micro-RNAs: The Most Recent and Relevant Biomarkers in the Early Diagnosis of Hepatocellular Carcinoma

  • Angela Cozma,
  • Adriana Fodor,
  • Romana Vulturar,
  • Adela-Viviana Sitar-Tăut,
  • Olga Hilda Orăşan,
  • Flaviu Mureşan,
  • Cezar Login and
  • Ramona Suharoschi

19 September 2019

Hepatocellular carcinoma (HCC) is a frequently encountered cancer type, and its alarming incidence is explained by genetic and epigenetic alterations. Epigenetic changes may represent diagnostic and prognostic biomarkers of HCC. In this review we dis...

  • Article
  • Open Access
16 Citations
2,851 Views
10 Pages

Surgical Treatment of Infective Endocarditis in Pulmonary Position—15 Years Single Centre Experience

  • Daina Liekiene,
  • Laurynas Bezuska,
  • Palmyra Semeniene,
  • Rasa Cypiene,
  • Virgilijus Lebetkevicius,
  • Virgilijus Tarutis,
  • Jurate Barysiene,
  • Kestutis Rucinskas and
  • Vytautas Sirvydis

19 September 2019

Background and Objectives: Infective endocarditis in the pulmonary position is a rare disease. Isolated pulmonary valve endocarditis is extremely rare. The aim of our study was to assess patients who were treated surgically for pulmonary endocarditis...

  • Review
  • Open Access
170 Citations
28,191 Views
11 Pages

18 September 2019

The history of hormone replacement therapy (HRT) started in the 1960s, with very high popularity in the 1990s. The first clinical trials on HRT and chronic postmenopausal conditions were started in the USA in the late 1990s. After the announcement of...

  • Commentary
  • Open Access
12 Citations
14,845 Views
14 Pages

Naturopathy as a Model of Prevention-Oriented, Patient-Centered Primary Care: A Disruptive Innovation in Health Care

  • Ryan Bradley,
  • Joanna Harnett,
  • Kieran Cooley,
  • Erica McIntyre,
  • Joshua Goldenberg and
  • Jon Adams

18 September 2019

Background and Objective: The concept of a “disruptive innovation,” recently extended to health care, refers to an emerging technology that represents a new market force combined with a new value system, that eventually displaces some, or...

  • Article
  • Open Access
5 Citations
3,859 Views
9 Pages

Vitamin A Enhances Macrophages Activity Against B16-F10 Malignant Melanocytes: A New Player for Cancer Immunotherapy?

  • Sofia Oliveira,
  • José Costa,
  • Isabel Faria,
  • Susana G. Guerreiro and
  • Rúben Fernandes

18 September 2019

Background and objectives: The incidence of cutaneous melanoma has been increasing. Melanoma is an aggressive form of skin cancer irresponsive to radiation and chemotherapy, rendering this cancer a disease with poor prognosis: In order to surpass som...

  • Article
  • Open Access
3 Citations
2,543 Views
9 Pages

18 September 2019

Background and objectives: The light-curing unit is considered an essential piece of equipment in every dental office. This study was conducted to evaluate the effect of Light-Emitting Diodes (LEDs) by the light cure (LC) device on gingival tissues o...

  • Case Report
  • Open Access
25 Citations
9,171 Views
10 Pages

Gallstone Ileus: Management and Clinical Outcomes

  • Matas Jakubauskas,
  • Raminta Luksaite,
  • Audrius Sileikis,
  • Kestutis Strupas and
  • Tomas Poskus

17 September 2019

Background: Gallstone or biliary ileus is a late complication of gallstone disease. It accounts for 1%–4% of all bowel obstructions and is more common in elderly patients. The preferred treatment option is to mechanically remove the impacted st...

  • Article
  • Open Access
9 Citations
3,275 Views
8 Pages

17 September 2019

Background and Objectives: Obstructive sleep apnea syndrome (OSAS) is the most frequent sleep disorder, characterized by the repeated collapse of the upper respiratory tract during sleep. In this study, we aimed to determine the prevalence of OSAS in...

  • Article
  • Open Access
43 Citations
5,063 Views
8 Pages

17 September 2019

Background and objectives: Nonalcoholic fatty liver disease (NAFLD) is associated with multiple factors such as hypertension, diabetes, dyslipidemia, obesity, and hyperuricemia. We aim to investigate the relationship between uric acid and NAFLD in a...

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Medicina - ISSN 1648-9144