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Open AccessReview

Measuring Daylight: A Review of Dosimetry in Daylight Photodynamic Therapy

1
Photobiology Unit, NHS Tayside, Ninewells Hospital, Dundee DD1 9SY, UK
2
The Scottish Photodynamic Therapy Centre, Dundee DD1 9SY, UK
3
School of Medicine, University of Dundee, Dundee DD1 9SY, UK
4
Public Health England, Didcot OX11 0RQ, UK
*
Author to whom correspondence should be addressed.
Pharmaceuticals 2019, 12(4), 143; https://doi.org/10.3390/ph12040143
Received: 14 August 2019 / Revised: 5 September 2019 / Accepted: 17 September 2019 / Published: 20 September 2019
(This article belongs to the Special Issue Photodynamic Therapy 2019)
Successful daylight photodynamic therapy (DPDT) relies on the interaction of light, photosensitisers and oxygen. Therefore, the ‘dose’ of light that a patient receives during treatment is a clinically relevant quantity, with a minimum dose for effective treatment recommended in the literature. However, there are many different light measurement methods used in the published literature, which may lead to confusion surrounding reliable and traceable dose measurement in DPDT, and what the most appropriate method of light measurement in DPDT might be. Furthermore, for the majority of practitioners who do not carry out any formal dosimetry and for the patients receiving DPDT, building confidence in the evidence supporting this important treatment option is of key importance. This review seeks to clarify the methodology of DPDT and discusses the literature relating to DPDT dosimetry. View Full-Text
Keywords: daylight; photodynamic therapy; dosimetry; actinic keratosis; sunscreen daylight; photodynamic therapy; dosimetry; actinic keratosis; sunscreen
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MDPI and ACS Style

O’Mahoney, P.; Khazova, M.; Eadie, E.; Ibbotson, S. Measuring Daylight: A Review of Dosimetry in Daylight Photodynamic Therapy. Pharmaceuticals 2019, 12, 143.

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