Next Article in Journal
2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, 18F-Labeling and Preclinical PET Imaging
Next Article in Special Issue
The Importance of Iron Status for Young Children in Low- and Middle-Income Countries: A Narrative Review
Previous Article in Journal
Inflammation and Depression: A Nervous Plea for Psychiatry to Not Become Immune to Interpretation
Previous Article in Special Issue
Neurodegeneration with Brain Iron Accumulation Disorders: Valuable Models Aimed at Understanding the Pathogenesis of Iron Deposition
Review

Iron in Lung Pathology

1
Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA
2
Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA
*
Author to whom correspondence should be addressed.
Pharmaceuticals 2019, 12(1), 30; https://doi.org/10.3390/ph12010030
Received: 14 December 2018 / Revised: 30 January 2019 / Accepted: 10 February 2019 / Published: 15 February 2019
(This article belongs to the Special Issue Iron as Therapeutic Targets in Human Diseases)
The lung presents a unique challenge for iron homeostasis. The entire airway is in direct contact with the environment and its iron particulate matter and iron-utilizing microbes. However, the homeostatic and adaptive mechanisms of pulmonary iron regulation are poorly understood. This review provides an overview of systemic and local lung iron regulation, as well as the roles of iron in the development of lung infections, airway disease, and lung injury. These mechanisms provide an important foundation for the ongoing development of therapeutic applications. View Full-Text
Keywords: hepcidin; iron; lung; acute lung injury; COPD; lung infection; cystic fibrosis hepcidin; iron; lung; acute lung injury; COPD; lung infection; cystic fibrosis
Show Figures

Figure 1

MDPI and ACS Style

Zhang, V.; Nemeth, E.; Kim, A. Iron in Lung Pathology. Pharmaceuticals 2019, 12, 30. https://doi.org/10.3390/ph12010030

AMA Style

Zhang V, Nemeth E, Kim A. Iron in Lung Pathology. Pharmaceuticals. 2019; 12(1):30. https://doi.org/10.3390/ph12010030

Chicago/Turabian Style

Zhang, Vida; Nemeth, Elizabeta; Kim, Airie. 2019. "Iron in Lung Pathology" Pharmaceuticals 12, no. 1: 30. https://doi.org/10.3390/ph12010030

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop