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Sensors 2018, 18(9), 2901;

Ruthenium Oxide Nanorods as Potentiometric pH Sensor for Organs-On-Chip Purposes

BIOS Lab on a Chip Group, Technical Medical Centre, MESA + Institute for Nanotechnology, and Max Planck Center for Complex Fluid Dynamics, University of Twente, 7522 NB Enschede, The Netherlands
Author to whom correspondence should be addressed.
Received: 10 June 2018 / Revised: 23 August 2018 / Accepted: 28 August 2018 / Published: 1 September 2018
(This article belongs to the Special Issue Potentiometric Chemical Sensors)
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A ruthenium oxide (RuOx) sensor for potentiometric pH sensing is currently being developed for organs-on-chip purposes. The sensor was fabricated from a Ru(OH)3 precursor, resulting in RuOx nanorods after heating. An open-circuit potential of the RuOx electrode showed a near-Nernstian response of −58.05 mV/pH, with good selectivity against potentially interfering ions (lithium, sulfate, chloride, and calcium ions). The preconditioned electrode (stored in liquid) had a long-term drift of −0.8 mV/h, and its response rate was less than 2 s. Sensitivity to oxygen was observed at an order of magnitude lower than other reported metal-oxide pH sensors. Together with miniaturizability, the RuOx pH sensor proves to be a suitable pH sensor for organs-on-chip studies. View Full-Text
Keywords: ruthenium oxide; potentiometric sensor; pH sensor; organs-on-chip; lab-on-chip ruthenium oxide; potentiometric sensor; pH sensor; organs-on-chip; lab-on-chip

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Tanumihardja, E.; Olthuis, W.; van den Berg, A. Ruthenium Oxide Nanorods as Potentiometric pH Sensor for Organs-On-Chip Purposes. Sensors 2018, 18, 2901.

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