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Sensors 2018, 18(8), 2625; https://doi.org/10.3390/s18082625

Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia

1
Electronics and Communication Department, College of Engineering, Universiti Tenaga Nasional, KM-7 Jalan Uniten-Ikram, 43000 Kajang, Selangor, Malaysia
2
Institute of Power Electronics (IPE), College of Engineering, Universiti Tenaga Nasional, KM-7 Jalan Uniten-Ikram, 43000 Kajang, Selangor, Malaysia
3
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia
4
Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
*
Author to whom correspondence should be addressed.
Received: 27 June 2018 / Revised: 18 July 2018 / Accepted: 18 July 2018 / Published: 10 August 2018
(This article belongs to the Special Issue Microfluidic Sensors 2018)
Full-Text   |   PDF [1993 KB, uploaded 10 August 2018]   |  

Abstract

Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection. View Full-Text
Keywords: microfluidic; iron deficiency anemia; point-of-care; all-in-one microfluidic; iron deficiency anemia; point-of-care; all-in-one
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Yap, B.K.; M.Soair, S.N.; Talik, N.A.; Lim, W.F.; Mei I, L. Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia. Sensors 2018, 18, 2625.

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