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Volume 24
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10.3390/ijms24087473
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Review

Biodegradable Polymers and Polymer Composites with Antibacterial Properties

by
Anna Smola-Dmochowska
1,
Kamila Lewicka
2,
Alicja Macyk
3,
Piotr Rychter
2,
Elżbieta Pamuła
3,* and
Piotr Dobrzyński
1,2,*
1
Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 Marii Curie-Skłodowskiej Str., 41-819 Zabrze, Poland
2
Faculty of Science and Technology, Jan Dlugosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Czestochowa, Poland
3
Department of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, 30 Mickiewicza Av., 30-059 Kraków, Poland
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2023, 24(8), 7473; https://doi.org/10.3390/ijms24087473
Submission received: 9 March 2023 / Revised: 5 April 2023 / Accepted: 7 April 2023 / Published: 18 April 2023
(This article belongs to the Special Issue Polymers, Polymer Blends, and Polymeric Drug Release Systems with Antiviral or Antibacterial Effect)
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Abstract

Antibiotic resistance is one of the greatest threats to global health and food security today. It becomes increasingly difficult to treat infectious disorders because antibiotics, even the newest ones, are becoming less and less effective. One of the ways taken in the Global Plan of Action announced at the World Health Assembly in May 2015 is to ensure the prevention and treatment of infectious diseases. In order to do so, attempts are made to develop new antimicrobial therapeutics, including biomaterials with antibacterial activity, such as polycationic polymers, polypeptides, and polymeric systems, to provide non-antibiotic therapeutic agents, such as selected biologically active nanoparticles and chemical compounds. Another key issue is preventing food from contamination by developing antibacterial packaging materials, particularly based on degradable polymers and biocomposites. This review, in a cross-sectional way, describes the most significant research activities conducted in recent years in the field of the development of polymeric materials and polymer composites with antibacterial properties. We particularly focus on natural polymers, i.e., polysaccharides and polypeptides, which present a mechanism for combating many highly pathogenic microorganisms. We also attempt to use this knowledge to obtain synthetic polymers with similar antibacterial activity.
Keywords: biodegradable polymers; antibacterial polymers; polysaccharides; peptides; antimicrobial peptides; polycarbonates; polyesters; biomaterials; antibacterial composites; food packaging biodegradable polymers; antibacterial polymers; polysaccharides; peptides; antimicrobial peptides; polycarbonates; polyesters; biomaterials; antibacterial composites; food packaging

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MDPI and ACS Style

Smola-Dmochowska, A.; Lewicka, K.; Macyk, A.; Rychter, P.; Pamuła, E.; Dobrzyński, P. Biodegradable Polymers and Polymer Composites with Antibacterial Properties. Int. J. Mol. Sci. 2023, 24, 7473. https://doi.org/10.3390/ijms24087473

AMA Style

Smola-Dmochowska A, Lewicka K, Macyk A, Rychter P, Pamuła E, Dobrzyński P. Biodegradable Polymers and Polymer Composites with Antibacterial Properties. International Journal of Molecular Sciences. 2023; 24(8):7473. https://doi.org/10.3390/ijms24087473

Chicago/Turabian Style

Smola-Dmochowska, Anna, Kamila Lewicka, Alicja Macyk, Piotr Rychter, Elżbieta Pamuła, and Piotr Dobrzyński. 2023. "Biodegradable Polymers and Polymer Composites with Antibacterial Properties" International Journal of Molecular Sciences 24, no. 8: 7473. https://doi.org/10.3390/ijms24087473

APA Style

Smola-Dmochowska, A., Lewicka, K., Macyk, A., Rychter, P., Pamuła, E., & Dobrzyński, P. (2023). Biodegradable Polymers and Polymer Composites with Antibacterial Properties. International Journal of Molecular Sciences, 24(8), 7473. https://doi.org/10.3390/ijms24087473

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