Next Article in Journal
Properties of Ginkgo biloba L.: Antioxidant Characterization, Antimicrobial Activities, and Genomic MicroRNA Based Marker Fingerprints
Next Article in Special Issue
Differential Urinary Proteome Analysis for Predicting Prognosis in Type 2 Diabetes Patients with and without Renal Dysfunction
Previous Article in Journal
Hyaluronan-Metal Gold Nanoparticle Hybrids for Targeted Tumor Cell Therapy
Previous Article in Special Issue
Glomerular Deposition of Nephritis-Associated Plasmin Receptor (NAPlr) and Related Plasmin Activity: Key Diagnostic Biomarkers of Bacterial Infection-related Glomerulonephritis
Review

Role of the Furosemide Stress Test in Renal Injury Prognosis

1
Department of Nephrology, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain
2
Department of Intensive Care Medicine, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain
3
Department of Cardiac Surgery, Hospital Clinico Universitario de Valladolid, 47003 Valladolid, Spain
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Int. J. Mol. Sci. 2020, 21(9), 3086; https://doi.org/10.3390/ijms21093086
Received: 11 April 2020 / Revised: 23 April 2020 / Accepted: 24 April 2020 / Published: 27 April 2020
(This article belongs to the Special Issue Biomarkers of Renal Diseases)
Risk stratification and accurate patient prognosis are pending issues in the management of patients with kidney disease. The furosemide stress test (FST) has been proposed as a low-cost, fast, safe, and easy-to-perform test to assess tubular integrity, especially when compared to novel plasma and urinary biomarkers. However, the findings regarding its clinical use published so far provide insufficient evidence to recommend the generalized application of the test in daily clinical routine. Dosage, timing, and clinical outcomes of the FST proposed thus far have been significantly different, which further accentuates the need for standardization in the application of the test in order to facilitate the comparison of results between series. This review will summarize published research regarding the usefulness of the FST in different settings, providing the reader some insights about the possible implications of FST in clinical decision-making in patients with kidney disease and the challenges that research will have to address in the near future before widely applying the FST. View Full-Text
Keywords: acute kidney injury; renal biomarkers; furosemide stress test; functional assessment acute kidney injury; renal biomarkers; furosemide stress test; functional assessment
Show Figures

Graphical abstract

MDPI and ACS Style

Coca, A.; Aller, C.; Reinaldo Sánchez, J.; Valencia, A.L.; Bustamante-Munguira, E.; Bustamante-Munguira, J. Role of the Furosemide Stress Test in Renal Injury Prognosis. Int. J. Mol. Sci. 2020, 21, 3086. https://doi.org/10.3390/ijms21093086

AMA Style

Coca A, Aller C, Reinaldo Sánchez J, Valencia AL, Bustamante-Munguira E, Bustamante-Munguira J. Role of the Furosemide Stress Test in Renal Injury Prognosis. International Journal of Molecular Sciences. 2020; 21(9):3086. https://doi.org/10.3390/ijms21093086

Chicago/Turabian Style

Coca, Armando, Carmen Aller, Jimmy Reinaldo Sánchez, Ana L. Valencia, Elena Bustamante-Munguira, and Juan Bustamante-Munguira. 2020. "Role of the Furosemide Stress Test in Renal Injury Prognosis" International Journal of Molecular Sciences 21, no. 9: 3086. https://doi.org/10.3390/ijms21093086

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop