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Review

miRNAs in Lung Development and Diseases

1
Early Life Origins of Chronic Lung Diseases, Research Center Borstel, Leibniz Lung Center, Member of the German Center for Lung Research (DZL), 23845 Borstel, Germany
2
Institute for Experimental Medicine, Christian-Albrechts-Universität zu Kiel, 24118 Kiel, Germany
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(8), 2765; https://doi.org/10.3390/ijms21082765
Received: 20 March 2020 / Revised: 11 April 2020 / Accepted: 12 April 2020 / Published: 16 April 2020
(This article belongs to the Special Issue The Role of Non-Coding RNAs in Human Lung Health and Disease)
The development of the lung involves a diverse group of molecules that regulate cellular processes, organ formation, and maturation. The various stages of lung development are marked by accumulation of small RNAs that promote or repress underlying mechanisms, depending on the physiological environment in utero and postnatally. To some extent, the pathogenesis of various lung diseases is regulated by small RNAs. In this review, we discussed miRNAs regulation of lung development and diseases, that is, COPD, asthma, pulmonary fibrosis, and pulmonary arterial hypertension, and also highlighted possible connotations for human lung health. View Full-Text
Keywords: lung development; lung diseases; miRNA; human; mouse lung development; lung diseases; miRNA; human; mouse
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MDPI and ACS Style

Boateng, E.; Krauss-Etschmann, S. miRNAs in Lung Development and Diseases. Int. J. Mol. Sci. 2020, 21, 2765. https://doi.org/10.3390/ijms21082765

AMA Style

Boateng E, Krauss-Etschmann S. miRNAs in Lung Development and Diseases. International Journal of Molecular Sciences. 2020; 21(8):2765. https://doi.org/10.3390/ijms21082765

Chicago/Turabian Style

Boateng, Eistine, and Susanne Krauss-Etschmann. 2020. "miRNAs in Lung Development and Diseases" International Journal of Molecular Sciences 21, no. 8: 2765. https://doi.org/10.3390/ijms21082765

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