Novel Physiology and Definition of Poor Ovarian Response; Clinical Recommendations
1
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut 1107 2020, Lebanon
2
The Fertility Clinic Skive Regional Hospital, 7800 Skive, Denmark
3
Faculty of Health, Aarhus University, 8000 Aarhus C, Denmark
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(6), 2110; https://doi.org/10.3390/ijms21062110
Received: 30 December 2019
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Revised: 24 February 2020
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Accepted: 6 March 2020
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Published: 19 March 2020
(This article belongs to the Special Issue Novel Physiology and Molecular Pathology of Reproduction, Novel Treatments of Infertility)
Poor ovarian response (POR) to controlled ovarian stimulation (OS) presents a major challenge in assisted reproduction. The Bologna criteria represented the first serious attempt to set clear criteria for the definition of POR. However, the Bologna criteria were questioned because of the persistent heterogeneity among POR patients and the inability to provide management strategies. Based on these facts, a more recent classification, the POSEIDON (Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number) classification, was developed to provide a homogeneous and refined definition of POR that significantly reduces the heterogeneity of the Bologna criteria definition of POR and helps in the clinical handling and counseling of patients. In this review, we discuss the impact of the POSEIDON classification on the clinical management of patients with POR.
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MDPI and ACS Style
Abu-Musa, A.; Haahr, T.; Humaidan, P. Novel Physiology and Definition of Poor Ovarian Response; Clinical Recommendations. Int. J. Mol. Sci. 2020, 21, 2110. https://doi.org/10.3390/ijms21062110
AMA Style
Abu-Musa A, Haahr T, Humaidan P. Novel Physiology and Definition of Poor Ovarian Response; Clinical Recommendations. International Journal of Molecular Sciences. 2020; 21(6):2110. https://doi.org/10.3390/ijms21062110
Chicago/Turabian StyleAbu-Musa, Antoine, Thor Haahr, and Peter Humaidan. 2020. "Novel Physiology and Definition of Poor Ovarian Response; Clinical Recommendations" International Journal of Molecular Sciences 21, no. 6: 2110. https://doi.org/10.3390/ijms21062110
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