Next Article in Journal
RNA Splicing Defects in Hypertrophic Cardiomyopathy: Implications for Diagnosis and Therapy
Next Article in Special Issue
Platelet Features and Derivatives in Osteoporosis: A Rational and Systematic Review on the Best Evidence
Previous Article in Journal
Human-Induced Pluripotent Stem Cells and Herbal Small-Molecule Drugs for Treatment of Alzheimer’s Disease
Previous Article in Special Issue
The MICELI (MICrofluidic, ELectrical, Impedance): Prototyping a Point-of-Care Impedance Platelet Aggregometer
Open AccessReview

Platelet Concentrates in Musculoskeletal Medicine

1
Laboratorio di Immunoreumatologia e rigenerazione tissutale, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy
2
Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum-University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(4), 1328; https://doi.org/10.3390/ijms21041328
Received: 16 December 2019 / Revised: 29 January 2020 / Accepted: 6 February 2020 / Published: 16 February 2020
(This article belongs to the Special Issue Molecular Research on Platelet Activity in Health and Disease)
Platelet concentrates (PCs), mostly represented by platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are autologous biological blood-derived products that may combine plasma/platelet-derived bioactive components, together with fibrin-forming protein able to create a natural three-dimensional scaffold. These types of products are safely used in clinical applications due to the autologous-derived source and the minimally invasive application procedure. In this narrative review, we focus on three main topics concerning the use of platelet concentrate for treating musculoskeletal conditions: (a) the different procedures to prepare PCs, (b) the composition of PCs that is related to the type of methodological procedure adopted and (c) the clinical application in musculoskeletal medicine, efficacy and main limits of the different studies. View Full-Text
Keywords: platelet-rich plasma; platelet-rich fibrin; preparation; composition; musculoskeletal diseases platelet-rich plasma; platelet-rich fibrin; preparation; composition; musculoskeletal diseases
MDPI and ACS Style

Mariani, E.; Pulsatelli, L. Platelet Concentrates in Musculoskeletal Medicine. Int. J. Mol. Sci. 2020, 21, 1328.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop