Next Article in Journal
Long-Chain Saturated Fatty Acids, Palmitic and Stearic Acids, Enhance the Repair of Photosystem II
Next Article in Special Issue
Mimulus sRNAs Are Wound Responsive and Associated with Transgenerationally Plastic Genes but Rarely Both
Previous Article in Journal
Platelet Induced Functional Alteration of CD4+ and CD8+ T Cells in HNSCC
Previous Article in Special Issue
Application of the MSAP Technique to Evaluate Epigenetic Changes in Plant Conservation
Article

m6A RNA Methylation in Marine Plants: First Insights and Relevance for Biological Rhythms

1
Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy
2
Department of Marine Sciences, Tjärnö Marine Laboratory, University of Gothenburg, SE-45296 Strömstad, Sweden
3
Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici (NA), Italy
4
CCMar—Centre of Marine Sciences, University of Algarve, Campus of Gambelas, 8005-139 Faro, Portugal
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(20), 7508; https://doi.org/10.3390/ijms21207508
Received: 18 August 2020 / Revised: 29 September 2020 / Accepted: 9 October 2020 / Published: 12 October 2020
Circadian regulations are essential for enabling organisms to synchronize physiology with environmental light-dark cycles. Post-transcriptional RNA modifications still represent an understudied level of gene expression regulation in plants, although they could play crucial roles in environmental adaptation. N6-methyl-adenosine (m6A) is the most prevalent mRNA modification, established by “writer” and “eraser” proteins. It influences the clockwork in several taxa, but only few studies have been conducted in plants and none in marine plants. Here, we provided a first inventory of m6A-related genes in seagrasses and investigated daily changes in the global RNA methylation and transcript levels of writers and erasers in Cymodocea nodosa and Zostera marina. Both species showed methylation peaks during the dark period under the same photoperiod, despite exhibiting asynchronous changes in the m6A profile and related gene expression during a 24-h cycle. At contrasting latitudes, Z. marina populations displayed overlapping daily patterns of the m6A level and related gene expression. The observed rhythms are characteristic for each species and similar in populations of the same species with different photoperiods, suggesting the existence of an endogenous circadian control. Globally, our results indicate that m6A RNA methylation could widely contribute to circadian regulation in seagrasses, potentially affecting the photo-biological behaviour of these plants. View Full-Text
Keywords: marine plants; epitranscriptome; m6A-methylation; circadian clock; RNA methyltransferases; RNA demethylases; daily cycle; photoperiod; latitude marine plants; epitranscriptome; m6A-methylation; circadian clock; RNA methyltransferases; RNA demethylases; daily cycle; photoperiod; latitude
Show Figures

Graphical abstract

MDPI and ACS Style

Ruocco, M.; Ambrosino, L.; Jahnke, M.; Chiusano, M.L.; Barrote, I.; Procaccini, G.; Silva, J.; Dattolo, E. m6A RNA Methylation in Marine Plants: First Insights and Relevance for Biological Rhythms. Int. J. Mol. Sci. 2020, 21, 7508. https://doi.org/10.3390/ijms21207508

AMA Style

Ruocco M, Ambrosino L, Jahnke M, Chiusano ML, Barrote I, Procaccini G, Silva J, Dattolo E. m6A RNA Methylation in Marine Plants: First Insights and Relevance for Biological Rhythms. International Journal of Molecular Sciences. 2020; 21(20):7508. https://doi.org/10.3390/ijms21207508

Chicago/Turabian Style

Ruocco, Miriam, Luca Ambrosino, Marlene Jahnke, Maria L. Chiusano, Isabel Barrote, Gabriele Procaccini, João Silva, and Emanuela Dattolo. 2020. "m6A RNA Methylation in Marine Plants: First Insights and Relevance for Biological Rhythms" International Journal of Molecular Sciences 21, no. 20: 7508. https://doi.org/10.3390/ijms21207508

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop