Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions
Abstract
:1. Introduction
2. Results and Discussion
2.1. The Multimerisation of Parallel Quadruplexes
2.2. The Mutated Parallel Variants Are Uniform in Some Aspects and Diverse in Others
2.3. The DNA Concentration-Dependent Formation of Type 2 Multimolecular Structures Is Not Directly Reflected in CD
2.4. Parallel Quadruplexes Are Significantly More Affected by Guanine Lesions than the Antiparallel Ones
3. Materials and Methods
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
Abbreviations
G4 | Guanine quadruplex |
CD | Circular dichroism |
PAGE | Polyacrylamide gel electrophoresis |
SF | Stopped-flow |
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Bednářová, K.; Vorlíčková, M.; Renčiuk, D. Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions. Int. J. Mol. Sci. 2020, 21, 6123. https://doi.org/10.3390/ijms21176123
Bednářová K, Vorlíčková M, Renčiuk D. Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions. International Journal of Molecular Sciences. 2020; 21(17):6123. https://doi.org/10.3390/ijms21176123
Chicago/Turabian StyleBednářová, Klára, Michaela Vorlíčková, and Daniel Renčiuk. 2020. "Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions" International Journal of Molecular Sciences 21, no. 17: 6123. https://doi.org/10.3390/ijms21176123