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Serotonin in Health and Disease

Centre National de la Recherche Scientifique, UMR CNRS 5287, CEDEX F-33000 Bordeaux, France
Laboratory of Neurophysiology, Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, MSD2080 Msida, Malta
School of Biosciences, Neuroscience Division, Cardiff University, Cardiff CF10 3AX, UK
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(10), 3500;
Received: 27 April 2020 / Accepted: 13 May 2020 / Published: 15 May 2020
(This article belongs to the Special Issue Serotonin in Health and Disease)
The International Journal of Molecular Sciences Special Issue “Serotonin in health and diseases” covers several aspects of the multiple and still mysterious functions of serotonin (5-hydroxytryptamine; 5-HT). 5-HT is neurotransmitter acting in the central nervous system (CNS), blood factor, and neurohormone controlling the function of several peripheral organs. Beyond its widespread implication in physiology, the 5-HT system is involved in numerous diseases of the CNS (e.g., depression, anxiety, schizophrenia, obsessive-compulsive disorders, addiction, Parkinson’s disease) and peripheral organs (e.g., gastrointestinal disorders, cardiac arrhythmia, hypertension). The Special Issue includes 14 articles dealing with molecular and cellular effects of 5-HT in periphery and CNS, from functional aspects in lower animals to clinical practices. Beyond physiology, the Special Issue also covers the influence of 5-HT and its receptors in the mechanism of action of psychoactive molecules including antipsychotics, antidepressants, and drug of abuse. The recent progress made on the function and dysfunction of the 5-HT system will certainly increase the understanding of the widespread role of 5-HT ultimately leading to better apprehend its targeting in human diseases. View Full-Text
MDPI and ACS Style

De Deurwaerdère, P.; Di Giovanni, G. Serotonin in Health and Disease. Int. J. Mol. Sci. 2020, 21, 3500.

AMA Style

De Deurwaerdère P, Di Giovanni G. Serotonin in Health and Disease. International Journal of Molecular Sciences. 2020; 21(10):3500.

Chicago/Turabian Style

De Deurwaerdère, Philippe, and Giuseppe Di Giovanni. 2020. "Serotonin in Health and Disease" International Journal of Molecular Sciences 21, no. 10: 3500.

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