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Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention

1,2 and 3,*
Graduate School, Wuhan Sports University, Wuhan 430079, China
College of Sports Science and Technology, Wuhan Sports University, Wuhan 430205, China
Tianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Sport Training and Monitoring, College of Health Science, Wuhan Sports University, Wuhan 430079, China
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2018, 19(2), 405;
Received: 3 January 2018 / Revised: 26 January 2018 / Accepted: 27 January 2018 / Published: 30 January 2018
(This article belongs to the Collection Regulation by Non-Coding RNAs)
PDF [665 KB, uploaded 30 January 2018]


Skeletal muscle comprising approximately 40% of body weight is highly important for locomotion and metabolic homeostasis. The growth and regeneration of skeletal muscle are highly organized processes; thus, it is not surprising to reveal certain complexity during these regulatory processes. Recently, a large number of evidence indicate that microRNAs can result in obvious impacts on growth, regeneration and metabolism of skeletal muscle. In this review, recent research achievements of microRNAs in regulating myogenesis, atrophy and aging during exercise intervention are discussed, which will provide the guidance for developing potential applications of microRNAs in health promotion and rehabilitation of sports injuries. View Full-Text
Keywords: microRNA; myogenesis; muscle atrophy; exercise; sport injury microRNA; myogenesis; muscle atrophy; exercise; sport injury

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Zhang, S.; Chen, N. Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention. Int. J. Mol. Sci. 2018, 19, 405.

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