Potential Biomarkers for Predicting Congenital Cytomegalovirus Infection
Abstract
:1. Introduction
2. Cytomegalovirus-Specific Antibody Tests
3. Cytomegalovirus Immunoglobulin G Avidity Measurements
4. Epitope-Specific Antibody Detection
5. Cytomegalovirus DNA Polymerase Chain Reaction Assay
6. Assays for Measuring Cytomegalovirus-Specific, T Cell-Mediated Immunity
7. Imaging Examinations
8. Clinical Factors Associated with the Occurrence of Congenital Cytomegalovirus Infection
9. Neonatal Screening and Definitive Diagnosis of Congenital Cytomegalovirus Infection
10. Potential Strategies to Improve the Outcomes of Children with Congenital CMV Infection
11. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
Abbreviations
CMV | Cytomegalovirus |
PCR | Polymerase chain reaction |
FGR | Fetal growth restriction |
IgG | Immunoglobulin G |
IgM | Immunoglobulin M |
ROC | Receiver operating characteristic |
GW | Weeks of gestation |
PPV | Positive predictive value |
NPV | Negative predictive value |
gp | glycoproteins |
gB | glycoprotein B |
gH | glycoprotein H |
ELISA | Enzyme-linked immunosorbent assay |
OR | Odds ratio |
CI | Confidence interval |
ELISPOT | Enzyme-linked immunosorbent spot |
QFT | QuantiFERON |
MRI | Magnetic resonance imaging |
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Tanimura, K.; Yamada, H. Potential Biomarkers for Predicting Congenital Cytomegalovirus Infection. Int. J. Mol. Sci. 2018, 19, 3760. https://doi.org/10.3390/ijms19123760
Tanimura K, Yamada H. Potential Biomarkers for Predicting Congenital Cytomegalovirus Infection. International Journal of Molecular Sciences. 2018; 19(12):3760. https://doi.org/10.3390/ijms19123760
Chicago/Turabian StyleTanimura, Kenji, and Hideto Yamada. 2018. "Potential Biomarkers for Predicting Congenital Cytomegalovirus Infection" International Journal of Molecular Sciences 19, no. 12: 3760. https://doi.org/10.3390/ijms19123760