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Int. J. Mol. Sci. 2017, 18(4), 814;

Bioethics of Clinical Applications of Stem Cells

Bioethics Unit, Office of the President, National Institute of Health, Via Giano della Bella 34, I-00162 Roma, Italy
Academic Editor: Maurizio Muraca
Received: 27 January 2017 / Revised: 7 April 2017 / Accepted: 10 April 2017 / Published: 12 April 2017
(This article belongs to the Special Issue Stem Cell Research)
Full-Text   |   PDF [187 KB, uploaded 12 April 2017]


The clinical applications of stem cells pose a multitude of problems, including safety, efficacy, information and consent, the right to unproven treatments, the “right to try”, costs, access, sustainability, scientific scrupulousness, patents and regulatory aspects, to name but a few. This article does not address individual issues, but rather introduces and discusses some of the possible approaches to solving the problems. The first part compares the consequentialist and deontological approaches, offering an overview of “top–down” and “bottom–up” models and proposing the principles of personalism as applied in clinical settings. The second part of the article suggests practical frameworks for organising the ethical issues, focusing in particular on the medical indications, patient preferences, quality of life, and contextual features. View Full-Text
Keywords: bioethics; clinical ethics; stem cells bioethics; clinical ethics; stem cells
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Petrini, C. Bioethics of Clinical Applications of Stem Cells. Int. J. Mol. Sci. 2017, 18, 814.

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