Localized Therapeutic Approaches Based on Micro/Nanofibers for Cancer Treatment
Abstract
:1. Introduction
2. Diagnostic
3. Cancer Therapies
4. Local and Systemic Drug Delivery Systems
4.1. Fibrous Structures as Localized Drug Delivery Systems for Cancer Treatment
Fiber | Nanoparticle | Released Drug | Type of Cancer | Ref. |
---|---|---|---|---|
CH | Silver | ---- | ---- | [54] |
CH-PVA | ---- | DOX | Ovarian | [55] |
CH | ---- | Gemcitabine | Pancreatic | [56] |
CH | ---- | Berberine | Cervical | [57] |
CH-PVA | ---- | HAp/DOX | Bone cancer | [58] |
CH-PU | MIL-53 | Temozolomide and PTX | --- | [59] |
PVA-Silk | ---- | DOX | Breast | [60] |
PVA | ---- | Dacarbazine | Glioblastoma | [61] |
PCL-PVA | ---- | PTX | Colon | [62] |
PLGA | ---- | PTX | Brain | [63] |
PLGA | Gold | DOX | ---- | [64] |
PLGA | MSNs | Curcumin | Breast | [65] |
PCL-PLGA | ---- | DOX | ---- | [66] |
Poly(NIPAAm-co-HMAAm | MNPs | DOX | Melanoma | [67] |
CH | Fe3O4 | ---- | ---- | [68] |
PLGA | MIONs | Dopamine and bortezomib | ---- | [69] |
PLA | MNPs | Daunorubicin | Leukemia | [70] |
PCL | MIONs and carbogenic nanodots | DOX | ---- | [71] |
PCL | MNPs | PTX | --- | [72] |
Cellulose acetate | Fe3O4 | ---- | ---- | [73] |
PCL | Fe3O4 | DOX | --- | [74] |
PCL | Fe3O4 | --- | --- | [75] |
Cellulose | MNPs | DOX | ---- | [76] |
PCL | MNPs | DOX and 17-allylamino-17-desmethoxygeldanamycin | ---- | [77] |
N-isopropylacrylamide and N-hydroxymethylacrylamide | MNPs | Metformin | Skin melanoma | [78] |
PCL | MNPs | DOX | ---- | [79] |
4.1.1. Chitosan Fibrous Structures as Localized Drug Delivery Systems for Cancer Treatment
4.1.2. Polyvinyl Alcohol Fibrous Structures as Localized Drug Delivery Systems for Cancer Treatment
4.1.3. Poly(lactic-co-glycolic acid) Fibrous Structures as Localized Drug Delivery Systems for Cancer Treatment
4.1.4. Magnetic NPs Combined with Fibrous Structures as Localized Drug Delivery Systems for Cancer Treatment
4.2. Nanofibers Theranostic Drug Delivery Systems for Cancer Treatment
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Fe3O4 (wt%) | ΔT (°C) |
---|---|
5 | 21.0 ± 0.4 |
9 | 25.2 ± 0.3 |
13 | 27.1 ± 0.5 |
17 | 31.1 ± 0.2 |
21 | 36.4 ± 0.3 |
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Alves, D.; Araújo, J.C.; Fangueiro, R.; Ferreira, D.P. Localized Therapeutic Approaches Based on Micro/Nanofibers for Cancer Treatment. Molecules 2023, 28, 3053. https://doi.org/10.3390/molecules28073053
Alves D, Araújo JC, Fangueiro R, Ferreira DP. Localized Therapeutic Approaches Based on Micro/Nanofibers for Cancer Treatment. Molecules. 2023; 28(7):3053. https://doi.org/10.3390/molecules28073053
Chicago/Turabian StyleAlves, Diana, Joana C. Araújo, Raul Fangueiro, and Diana P. Ferreira. 2023. "Localized Therapeutic Approaches Based on Micro/Nanofibers for Cancer Treatment" Molecules 28, no. 7: 3053. https://doi.org/10.3390/molecules28073053