Next Article in Journal
Activation of the Nrf2 Pathway as a Therapeutic Strategy for ALS Treatment
Next Article in Special Issue
Supercritical CO2 Extraction of Triterpenoids from Chaga Sterile Conk of Inonotus obliquus
Previous Article in Journal
Relative Stability of Boron Planar Clusters in Diatomic Molecular Model
Previous Article in Special Issue
Supercritical CO2 Extraction of Palladium Oxide from an Aluminosilicate-Supported Catalyst Enhanced by a Combination of Complexing Polymers and Piperidine
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Molecules
Volume 27
Issue 5
10.3390/molecules27051470
molecules-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Molecular Distillation of Lavender Supercritical Extracts: Physicochemical and Antimicrobial Characterization of Feedstocks and Assessment of Distillates Enriched with Oxygenated Fragrance Components

by
Agnieszka Dębczak
1,*,
Katarzyna Tyśkiewicz
1,
Zygmunt Fekner
1,
Piotr Kamiński
1,
Grzegorz Florkowski
1,
Marcin Konkol
1,
Edward Rój
1,
Agnieszka Grzegorczyk
2 and
Anna Malm
2
1
Łukasiewicz Research Network—New Chemical Syntheses Institute, Al. Tysiąclecia Państwa Polskiego 13A, 24-110 Puławy, Poland
2
Chair and Department of Pharmaceutical Microbiology, Medical University of Lublin, 1 Chodźki Str., 20-093 Lublin, Poland
*
Author to whom correspondence should be addressed.
Molecules 2022, 27(5), 1470; https://doi.org/10.3390/molecules27051470
Submission received: 2 February 2022 / Revised: 18 February 2022 / Accepted: 20 February 2022 / Published: 22 February 2022
(This article belongs to the Special Issue Chemical Applications of Supercritical Fluids)
Browse Figures
Review Reports Versions Notes

Abstract

Lavandula angustifolia is one of the most widely cultivated non-food crops used in the production of essential oil; it is used in perfumery, aromatherapy, pharmaceutical preparations, and food ingredients. In this study, supercritical fluid extraction (SFE) and molecular distillation (MD) were combined, primarily to enrich scCO2 extracts with lavender oxygenated monoterpenes, avoiding thermal degradation, hydrolysis, and solvent contamination, and maintaining the natural characteristics of the obtained oils. Molecular distillation was developed for the first time for the extraction of crucial lavender fragrance ingredients, i.e., from two scCO2 extracts obtained from dry flower stems of lavender cultivated in Poland and Bulgaria. The best results for high-quality distillates were obtained at 85 °C (EVT) and confirmed that linalyl acetate content increased from 51.54 mg/g (initial Bulgarian lavender extract, L-Bg-E) and 89.53 mg/g (initial Polish lavender extract, L-Pl-E) to 118.41 and 185.42 mg/g, respectively, corresponding to increases of 2.3 and 2.1 times in both distillate streams, respectively. The distillates, light oils, and extracts from lavender were also evaluated for their antimicrobial properties by determining the minimum inhibitory concentration (MIC) by the broth microdilution method. Generally, Gram-positive bacteria and Candida spp. were more sensitive to all distilled fractions and extracts than Escherichia coli (Gram-negative bacteria).
Keywords: antibacterial and antifungal activity; coumarins; lavender; molecular distillation; natural wax ingredients; oxygenated terpenes; pilot-scale SFE antibacterial and antifungal activity; coumarins; lavender; molecular distillation; natural wax ingredients; oxygenated terpenes; pilot-scale SFE

Share and Cite

MDPI and ACS Style

Dębczak, A.; Tyśkiewicz, K.; Fekner, Z.; Kamiński, P.; Florkowski, G.; Konkol, M.; Rój, E.; Grzegorczyk, A.; Malm, A. Molecular Distillation of Lavender Supercritical Extracts: Physicochemical and Antimicrobial Characterization of Feedstocks and Assessment of Distillates Enriched with Oxygenated Fragrance Components. Molecules 2022, 27, 1470. https://doi.org/10.3390/molecules27051470

AMA Style

Dębczak A, Tyśkiewicz K, Fekner Z, Kamiński P, Florkowski G, Konkol M, Rój E, Grzegorczyk A, Malm A. Molecular Distillation of Lavender Supercritical Extracts: Physicochemical and Antimicrobial Characterization of Feedstocks and Assessment of Distillates Enriched with Oxygenated Fragrance Components. Molecules. 2022; 27(5):1470. https://doi.org/10.3390/molecules27051470

Chicago/Turabian Style

Dębczak, Agnieszka, Katarzyna Tyśkiewicz, Zygmunt Fekner, Piotr Kamiński, Grzegorz Florkowski, Marcin Konkol, Edward Rój, Agnieszka Grzegorczyk, and Anna Malm. 2022. "Molecular Distillation of Lavender Supercritical Extracts: Physicochemical and Antimicrobial Characterization of Feedstocks and Assessment of Distillates Enriched with Oxygenated Fragrance Components" Molecules 27, no. 5: 1470. https://doi.org/10.3390/molecules27051470

APA Style

Dębczak, A., Tyśkiewicz, K., Fekner, Z., Kamiński, P., Florkowski, G., Konkol, M., Rój, E., Grzegorczyk, A., & Malm, A. (2022). Molecular Distillation of Lavender Supercritical Extracts: Physicochemical and Antimicrobial Characterization of Feedstocks and Assessment of Distillates Enriched with Oxygenated Fragrance Components. Molecules, 27(5), 1470. https://doi.org/10.3390/molecules27051470

Article Metrics

Back to TopTop