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Review

An Overview of the Potential Therapeutic Applications of Essential Oils

1
Health Sciences Division, Abu Dhabi Women’s College, Higher Colleges of Technology, 41012 Abu Dhabi, UAE
2
Department of Avian Disease Research and Diagnostic, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj 31585-854, Iran
3
Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, 43400 Selangor, Malaysia
4
Dubai Colleges, Higher Colleges of Technology, 17258 Dubai, UAE
*
Author to whom correspondence should be addressed.
Academic Editor: Vivian Tullio
Molecules 2021, 26(3), 628; https://doi.org/10.3390/molecules26030628
Received: 2 December 2020 / Revised: 7 January 2021 / Accepted: 10 January 2021 / Published: 26 January 2021
The emergence of antimicrobial resistance (AMR) has urged researchers to explore therapeutic alternatives, one of which includes the use of natural plant products such as essential oils (EO). In fact, EO obtained from clove, oregano, thymus, cinnamon bark, rosemary, eucalyptus, and lavender have been shown to present significant inhibitory effects on bacteria, fungi, and viruses; many studies have been done to measure EO efficacy against microorganisms. The strategy of combinatory effects via conventional and non-conventional methods revealed that the combined effects of EO–EO or EO–antibiotic exhibit enhanced efficacy. This paper aims to review the antimicrobial effects of EO, modes of EO action (membrane disruption, efflux inhibition, increase membrane permeability, and decrease in intracellular ATP), and their compounds’ potential as effective agents against bacteria, fungi, and viruses. It is hoped that the integration of EO applications in this work can be used to consider EO for future clinical applications. View Full-Text
Keywords: essential oils; antimicrobial activity; oregano; thymol; carvacrol; cinnamon bark; synergistic activity; genomics; proteomics essential oils; antimicrobial activity; oregano; thymol; carvacrol; cinnamon bark; synergistic activity; genomics; proteomics
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MDPI and ACS Style

Aljaafari, M.N.; AlAli, A.O.; Baqais, L.; Alqubaisy, M.; AlAli, M.; Molouki, A.; Ong-Abdullah, J.; Abushelaibi, A.; Lai, K.-S.; Lim, S.-H.E. An Overview of the Potential Therapeutic Applications of Essential Oils. Molecules 2021, 26, 628. https://doi.org/10.3390/molecules26030628

AMA Style

Aljaafari MN, AlAli AO, Baqais L, Alqubaisy M, AlAli M, Molouki A, Ong-Abdullah J, Abushelaibi A, Lai K-S, Lim S-HE. An Overview of the Potential Therapeutic Applications of Essential Oils. Molecules. 2021; 26(3):628. https://doi.org/10.3390/molecules26030628

Chicago/Turabian Style

Aljaafari, Mariam N., Asma O. AlAli, Laila Baqais, Maream Alqubaisy, Mudhi AlAli, Aidin Molouki, Janna Ong-Abdullah, Aisha Abushelaibi, Kok-Song Lai, and Swee-Hua E. Lim 2021. "An Overview of the Potential Therapeutic Applications of Essential Oils" Molecules 26, no. 3: 628. https://doi.org/10.3390/molecules26030628

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