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An Overview of the Potential Therapeutic Applications of Essential Oils
Review

Antifungal Properties of Essential Oils and Their Compounds for Application in Skin Fungal Infections: Conventional and Nonconventional Approaches

1
Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia No.1, Jalan Setia Murni U13/52, Seksyen U13 Setia Alam, Shah Alam 40170, Malaysia
2
Department of Biology, Faculty of Applied Science, Universiti Teknologi MARA (Perlis Branch), Arau 02600, Malaysia
3
Cancer Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, No.1, Jalan Setia Murni U13/52, Seksyen U13 Setia Alam, Shah Alam 40170, Malaysia
*
Authors to whom correspondence should be addressed.
Academic Editors: Vivian Tullio, Alessandra Guerrini and Domenico Cautela
Molecules 2021, 26(4), 1093; https://doi.org/10.3390/molecules26041093
Received: 30 December 2020 / Revised: 29 January 2021 / Accepted: 31 January 2021 / Published: 19 February 2021
Essential oils (EOs) are known to have varying degrees of antimicrobial properties that are mainly due to the presence of bioactive compounds. These include antiviral, nematicidal, antifungal, insecticidal and antioxidant properties. This review highlights the potential of EOs and their compounds for application as antifungal agents for the treatment of skin diseases via conventional and nonconventional approaches. A search was conducted using three databases (Scopus, Web of Science, Google Scholar), and all relevant articles from the period of 2010–2020 that are freely available in English were extracted. In our findings, EOs with a high percentage of monoterpenes showed strong ability as potential antifungal agents. Lavandula sp., Salvia sp., Thymus sp., Citrus sp., and Cymbopogon sp. were among the various species found to show excellent antifungal properties against various skin diseases. Some researchers developed advanced formulations such as gel, semi-solid, and ointment bases to further evaluate the effectiveness of EOs as antifungal agents. To date, most studies on the application of EOs as antifungal agents were performed using in vitro techniques, and only a limited number pursued in vivo and intervention-based research. View Full-Text
Keywords: skin fungus; essential oils; in vitro; in vivo; intervention skin fungus; essential oils; in vitro; in vivo; intervention
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MDPI and ACS Style

Abd Rashed, A.; Rathi, D.-N.G.; Ahmad Nasir, N.A.H.; Abd Rahman, A.Z. Antifungal Properties of Essential Oils and Their Compounds for Application in Skin Fungal Infections: Conventional and Nonconventional Approaches. Molecules 2021, 26, 1093. https://doi.org/10.3390/molecules26041093

AMA Style

Abd Rashed A, Rathi D-NG, Ahmad Nasir NAH, Abd Rahman AZ. Antifungal Properties of Essential Oils and Their Compounds for Application in Skin Fungal Infections: Conventional and Nonconventional Approaches. Molecules. 2021; 26(4):1093. https://doi.org/10.3390/molecules26041093

Chicago/Turabian Style

Abd Rashed, Aswir, Devi-Nair G. Rathi, Nor A.H. Ahmad Nasir, and Ahmad Z. Abd Rahman 2021. "Antifungal Properties of Essential Oils and Their Compounds for Application in Skin Fungal Infections: Conventional and Nonconventional Approaches" Molecules 26, no. 4: 1093. https://doi.org/10.3390/molecules26041093

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