Next Article in Journal
Size Effect of Graphene Quantum Dots on Photoluminescence
Next Article in Special Issue
On the Low-Lying Electronically Excited States of Azobenzene Dimers: Transition Density Matrix Analysis
Previous Article in Journal
Activity of Compounds from Temperate Propolis against Trypanosoma brucei and Leishmania mexicana
Previous Article in Special Issue
Polarization Dependent Photoinduced Supramolecular Chirality in High-Performance Azo Materials
Article

Active Ester Functionalized Azobenzenes as Versatile Building Blocks

by 1,2,†, 1,2,† and 1,2,*
1
Institute for Analytical and Organic Chemistry, University of Bremen, Leobener Straße 7, D-28359 Bremen, Germany
2
MAPEX Center for Materials and Processes, University of Bremen, Bibliothekstraße 1, D-28359 Bremen, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editors: Estelle Léonard and Muriel Billamboz
Molecules 2021, 26(13), 3916; https://doi.org/10.3390/molecules26133916
Received: 31 May 2021 / Revised: 22 June 2021 / Accepted: 23 June 2021 / Published: 26 June 2021
(This article belongs to the Special Issue Azobenzene and Applications: From Catalysis to Biology)
Azobenzenes are important molecular switches that can still be difficult to functionalize selectively. A high yielding Pd-catalyzed cross-coupling method under mild conditions for the introduction of NHS esters to azobenzenes and diazocines has been established. Yields were consistently high with very few exceptions. The NHS functionalized azobenzenes react with primary amines quantitatively. These amines are ubiquitous in biological systems and in material science. View Full-Text
Keywords: azobenzene; diazocine; molecular switches; palladium-catalyzed carbonylation; photo-switchable NHS ester; N-hydroxysuccinimide; chemical biology azobenzene; diazocine; molecular switches; palladium-catalyzed carbonylation; photo-switchable NHS ester; N-hydroxysuccinimide; chemical biology
Show Figures

Graphical abstract

MDPI and ACS Style

Schultzke, S.; Walther, M.; Staubitz, A. Active Ester Functionalized Azobenzenes as Versatile Building Blocks. Molecules 2021, 26, 3916. https://doi.org/10.3390/molecules26133916

AMA Style

Schultzke S, Walther M, Staubitz A. Active Ester Functionalized Azobenzenes as Versatile Building Blocks. Molecules. 2021; 26(13):3916. https://doi.org/10.3390/molecules26133916

Chicago/Turabian Style

Schultzke, Sven, Melanie Walther, and Anne Staubitz. 2021. "Active Ester Functionalized Azobenzenes as Versatile Building Blocks" Molecules 26, no. 13: 3916. https://doi.org/10.3390/molecules26133916

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop