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Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds

School of Pharmacy and Food Sciences, Zhuhai College of Jilin University, Zhuhai 519041, China
School of Environment and Energy, South China University of Technology, Guangzhou 510006, China
Institute of Marine Biology, College of Oceanography, Hohai University, Nanjing 210017, China
Freshwater Fisheries Research Institute of Jiangsu Province, 79 Chating East Street, Nanjing 210017, China
School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, China
Authors to whom correspondence should be addressed.
Academic Editor: Roberto Fabiani
Molecules 2019, 24(23), 4286;
Received: 27 October 2019 / Revised: 21 November 2019 / Accepted: 24 November 2019 / Published: 25 November 2019
(This article belongs to the Special Issue Antitumoral Properties of Natural Products)
Seaweeds are some of the largest producers of biomass in the marine environment and are rich in bioactive compounds that are often used for human and animal health. Porphyran and carrageenan are natural compounds derived from red seaweeds. The former is a characteristic polysaccharide of Porphyra, while the latter is well known from Chondrus, Gigartina, and various Eucheuma species, all in Rhodophyceae. The two polysaccharides have been found to have anti-cancer activity by improving immunity and targeting key apoptotic molecules and therefore deemed as potential chemotherapeutic or chemopreventive agents. This review attempts to review the current study of anti-cancer activity and the possible mechanisms of porphyran and carrageenan derived from red seaweeds to various cancers, and their cooperative actions with other anti-cancer chemotherapeutic agents is also discussed. View Full-Text
Keywords: seaweed; porphyran; carrageenan; anti-cancer seaweed; porphyran; carrageenan; anti-cancer
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Liu, Z.; Gao, T.; Yang, Y.; Meng, F.; Zhan, F.; Jiang, Q.; Sun, X. Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds. Molecules 2019, 24, 4286.

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