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Article
Peer-Review Record

Determination of Lactoferrin in Camel Milk by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry Using an Isotope-Labeled Winged Peptide as Internal Standard

Molecules 2019, 24(22), 4199; https://doi.org/10.3390/molecules24224199
by Xia Li 1, Zengmei Li 1, Enmin Xu 2, Ling Chen 2, Hua Feng 1, Lu Chen 1, Ligang Deng 1,* and Dongliang Guo 1,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Molecules 2019, 24(22), 4199; https://doi.org/10.3390/molecules24224199
Submission received: 29 October 2019 / Revised: 15 November 2019 / Accepted: 16 November 2019 / Published: 19 November 2019

Round 1

Reviewer 1 Report

The authors proposed a method for the Determination of Lactoferrin in Camel Milk by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry Using an Isotope-Labeled Winged Peptide as Internal Standard. The manuscript is well present and the content is interesting, therefore It is recommended for publication after some minor correction.

81 format problem

The authors should provide all standard purity.

Figure 2 and 3 have very low resolution.

It’s not clear if the UPLC method optimized or if the authors just adapted already exist methods.

Author Response

 

 

Author Response File: Author Response.pdf

Reviewer 2 Report

Please make Figure 2 more visible. Increase the size, to compromise the space make Figure 1 smaller.

Line 118: For mass transition notation, please use an arrow

Line 176: Please add error bars for Figure 3

Line 190: Table 1. Units should be “mg/ 100 g” not “Mg/100 g”

Author Response

 

 

Author Response File: Author Response.pdf

This manuscript is a resubmission of an earlier submission. The following is a list of the peer review reports and author responses from that submission.


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