Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice
Abstract
:1. Introduction
2. Results
2.1. Acute Toxicity of Diosmetin
2.2. Dis Reduces Tumor Size in HCT-116 Colon Cancer Xenograft Nude Mice
2.3. Apoptotic Effects of Dis in HCT-116 Xenograft Nude Mice
3. Discussion
4. Materials and Methods
4.1. Compound and Cell Lines
4.2. Acute Toxicity
4.3. Human Colorectal Cancer Xenografts in Athymic Nude Mice
4.4. Western Blot
4.5. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Samples of the compounds are available from the authors. |
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Koosha, S.; Mohamed, Z.; Sinniah, A.; Alshawsh, M.A. Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice. Molecules 2019, 24, 2522. https://doi.org/10.3390/molecules24142522
Koosha S, Mohamed Z, Sinniah A, Alshawsh MA. Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice. Molecules. 2019; 24(14):2522. https://doi.org/10.3390/molecules24142522
Chicago/Turabian StyleKoosha, Sanaz, Zahurin Mohamed, Ajantha Sinniah, and Mohammed A. Alshawsh. 2019. "Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice" Molecules 24, no. 14: 2522. https://doi.org/10.3390/molecules24142522