Homogeneous Synthesis of Cationic Chitosan via New Avenue
AbstractUsing a solvent formed of alkali and urea, chitosan was successfully dissolved in a new solvent via the freezing–thawing process. Subsequently, quaternized chitosan (QC) was synthesized using 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTAC) as the cationic reagent under different incubation times and temperatures in a homogeneous system. QCs cannot be synthesized at temperatures above 60 °C, as gel formation will occur. The structure and properties of the prepared QC were characterized and quaternary groups were comfirmed to be successfully incorporated onto chitosan backbones. The degree of substitution (DS) ranged from 16.5% to 46.8% and the yields ranged from 32.6% to 89.7%, which can be adjusted by changing the molar ratio of the chitosan unit to CHPTAC and the reaction time. QCs inhibits the growth of Alicyclobacillus acidoterrestris effectively. Thus, this work offers a simple and green method of functionalizing chitosan and producing quaternized chitosan with an antibacterial effect for potential applications in the food industry. View Full-Text
Share & Cite This Article
Song, H.; Wu, H.; Li, S.; Tian, H.; Li, Y.; Wang, J. Homogeneous Synthesis of Cationic Chitosan via New Avenue. Molecules 2018, 23, 1921.
Song H, Wu H, Li S, Tian H, Li Y, Wang J. Homogeneous Synthesis of Cationic Chitosan via New Avenue. Molecules. 2018; 23(8):1921.Chicago/Turabian Style
Song, Huanlu; Wu, Hao; Li, ShuJing; Tian, Huafeng; Li, YanRu; Wang, JianGuo. 2018. "Homogeneous Synthesis of Cationic Chitosan via New Avenue." Molecules 23, no. 8: 1921.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.