Molecules 2018, 23(6), 1455; https://doi.org/10.3390/molecules23061455
Synergistic Effects of Resveratrol and Pyrimethanil against Botrytis cinerea on Grape
1
Department of Plant Pathology/Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China
2
College of Plant Protection, China Agricultural University, Beijing 100193, China
*
Authors to whom correspondence should be addressed.
Received: 26 April 2018 / Revised: 12 June 2018 / Accepted: 12 June 2018 / Published: 15 June 2018
(This article belongs to the Collection Phytoalexins: Fundamental Aspects and Applications)
Abstract
Botrytis cinerea is the pathogen of gray mold disease affecting a wide range of plant hosts, with consequential economic losses worldwide. The increased frequency of fungicide resistance of the pathogen challenges its disease management, and thus the development of alternative control strategies are urgently required. In this study, we showed excellent synergistic interactions between resveratrol and pyrimethanil. Significant synergistic values were recorded by the two-drug combination on the suppression of mycelial growth and conidia germination of B. cinerea. The combination of resveratrol and pyrimethanil caused malformation of mycelia. Moreover, the inoculation assay was conducted on table grape and consistent synergistic suppression of the two-drug combination was found in vivo. Our findings first revealed that the combination of resveratrol and pyrimethanil has synergistic effects against resistant B. cinerea and support the potential use of resveratrol as a promising adjuvant on the control of gray mold. View Full-TextKeywords:
adjuvant; antifungal activity; drug combination; gray mold; resistant isolate
▼
Figures
Figure 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
Share & Cite This Article
MDPI and ACS Style
Xu, D.; Yu, G.; Xi, P.; Kong, X.; Wang, Q.; Gao, L.; Jiang, Z. Synergistic Effects of Resveratrol and Pyrimethanil against Botrytis cinerea on Grape. Molecules 2018, 23, 1455.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
Related Articles
Article Metrics
Comments
[Return to top]
Molecules
EISSN 1420-3049
Published by MDPI AG, Basel, Switzerland
RSS
E-Mail Table of Contents Alert